chapter 10- MSK Flashcards
are males or females more affected with RA and SLE
females
are males or females more affected with gout
males
what is the most common cause of LTD in the US general population
arthritic disorders
are males or females more affected with OA
females
what other disease can DISH be associated with
diabetes. up to 40% of people with DISH have diabetes, possible related to insulin causing bone growth
how does RA frequently initially present
fatigue, morning stiffness, swelling and pain in several joints, disturbance of normal joint function
list the 6 factors associated with poor prognosis of RA
male gender, early functional disability, high titer of RF or antibodies to CPP, early development of radiologic erosion, extra-articular. manifestations, smoking
list some extra-articular manifestations of RA
rheumatoid nodule, vasculitis, cardiac disease/pericarditis, scleritis, Felty’s syndrome, pulmonary disease, dry eyes and mouth/ Sicca syndrome
what lab findings are often found with RA
anemia, elev PLT, elev ferritin, in addition to pos RF
is RA associated with increased mortality?
yes, when it is severe
what are markers of reduced survival with RA
poor functional capacity, multiple joint involvement, need for hospitalization
what is the most common cause of death in RA patients
cardiovascular disease
what are the 4 spondyloarthropathies
ankylosing spondylitis, psoriatic arthritis, arthritis of inflammatory bowel disease, reactive arthritis
do spondylarthropathies have positive RF
no
what are extra-articular manifestations of ankylosing spondylitis
iritis, rarely cardiac disorders such as heart block or carotid , rare pulmonary fibrosis
is reactive arthritis more common in males or females
males
what is the classic triad of reactive arthritis
- arthritis 2. urethritis/cervicitis 3. conjunctivitis/uveitis
what is clinical course and prognosis of SLE
some have mild illness with fever, fatigue, rash, arthritis. other have very serious disease with life-threatening real or neurologic disease. involvement of organs can occur
what are causes of death associated with SLE
active lupus with end-organ damage, infection, atherosclerotic complications
what is another name for scleroderma
systemic sclerosis
what is often first symptom of scleroderma
Raynaud’s phemenon
is scleroderma more common in males or females
females
an inflammatory disorder of the spine that can also involve the peripheral joints is: 1. ankylosing spondylitis 2. reactive arthritis 3. polyarteritis nodes 4. Raynaud’s phenomenon
- ankylosing spondylitis
all of the following are types of vasculitis EXCEPT: 1. polyarteritis nodosa 2. granulomatosis with polyangiitis 3. temporal arteritis 4. granulomatous enteritis
- granulmiatous enteritis
Is systemic sclerosis an autoimmune disease characterized by skin hardening?
yes
is systemic sclerosis effectively treated with penicillamine?
no
can systemic sclerosis cause scarring and fibrosis in the lungs?
yes
is late menopause a risk factor for OP
no
Which of the following is/are symptoms associated with Sjogren’s syndrome?
A. Difficulty swallowing
B. Joint stiffness
C. Rashes on the arms and legs
A, B and C
All of the following statements describe polymyositis except:
A. It is more common in females
B. It can be associated with an underlying malignancy
C. It can include a rash on the son exposed areas of the skin
It can include a rash on some exposed areas of the skin
Osteomalacia is most accurately described as
A. Tumor of the bone
B. Pain of the bone
C. Inflammation of the bone
D. defective mineralization of the skeletal matrix
D. A defective mineralization of the skeletal matrix
