chapter 10- MSK

Question 1

are males or females more affected with RA and SLE

Answer 1

females

Question 2

are males or females more affected with gout

Answer 2

males

Question 3

what is the most common cause of LTD in the US general population

Answer 3

arthritic disorders

Question 4

are males or females more affected with OA

Answer 4

females

Question 5

what other disease can DISH be associated with

Answer 5

diabetes. up to 40% of people with DISH have diabetes, possible related to insulin causing bone growth

Question 6

how does RA frequently initially present

Answer 6

fatigue, morning stiffness, swelling and pain in several joints, disturbance of normal joint function

Question 7

list the 6 factors associated with poor prognosis of RA

Answer 7

male gender, early functional disability, high titer of RF or antibodies to CPP, early development of radiologic erosion, extra-articular. manifestations, smoking

Question 8

list some extra-articular manifestations of RA

Answer 8

rheumatoid nodule, vasculitis, cardiac disease/pericarditis, scleritis, Felty’s syndrome, pulmonary disease, dry eyes and mouth/ Sicca syndrome

Question 9

what lab findings are often found with RA

Answer 9

anemia, elev PLT, elev ferritin, in addition to pos RF

Question 10

is RA associated with increased mortality?

Answer 10

yes, when it is severe

Question 11

what are markers of reduced survival with RA

Answer 11

poor functional capacity, multiple joint involvement, need for hospitalization

Question 12

what is the most common cause of death in RA patients

Answer 12

cardiovascular disease

Question 13

what are the 4 spondyloarthropathies

Answer 13

ankylosing spondylitis, psoriatic arthritis, arthritis of inflammatory bowel disease, reactive arthritis

Question 14

do spondylarthropathies have positive RF

Answer 14

no

Question 15

what are extra-articular manifestations of ankylosing spondylitis

Answer 15

iritis, rarely cardiac disorders such as heart block or carotid , rare pulmonary fibrosis

Question 16

is reactive arthritis more common in males or females

Answer 16

males

Question 17

what is the classic triad of reactive arthritis

Answer 17

1. arthritis 2. urethritis/cervicitis 3. conjunctivitis/uveitis

Question 18

what is clinical course and prognosis of SLE

Answer 18

some have mild illness with fever, fatigue, rash, arthritis. other have very serious disease with life-threatening real or neurologic disease. involvement of organs can occur

Question 19

what are causes of death associated with SLE

Answer 19

active lupus with end-organ damage, infection, atherosclerotic complications

Question 20

what is another name for scleroderma

Answer 20

systemic sclerosis

Question 21

what is often first symptom of scleroderma

Answer 21

Raynaud’s phemenon

Question 22

is scleroderma more common in males or females

Answer 22

females

Question 23

an inflammatory disorder of the spine that can also involve the peripheral joints is: 1. ankylosing spondylitis 2. reactive arthritis 3. polyarteritis nodes 4. Raynaud’s phenomenon

Answer 23

1. ankylosing spondylitis

Question 24

all of the following are types of vasculitis EXCEPT: 1. polyarteritis nodosa 2. granulomatosis with polyangiitis 3. temporal arteritis 4. granulomatous enteritis

Answer 24

4. granulmiatous enteritis

Question 25

Is systemic sclerosis an autoimmune disease characterized by skin hardening?

Answer 25

yes

Question 26

is systemic sclerosis effectively treated with penicillamine?

Answer 26

no

Question 27

can systemic sclerosis cause scarring and fibrosis in the lungs?

Answer 27

yes

Question 28

is late menopause a risk factor for OP

Answer 28

no

Question 29

Which of the following is/are symptoms associated with Sjogren’s syndrome?
A. Difficulty swallowing
B. Joint stiffness
C. Rashes on the arms and legs

Answer 29

A, B and C

Question 30

All of the following statements describe polymyositis except:
A. It is more common in females
B. It can be associated with an underlying malignancy
C. It can include a rash on the son exposed areas of the skin

Answer 30

It can include a rash on some exposed areas of the skin

Question 31

Osteomalacia is most accurately described as
A. Tumor of the bone
B. Pain of the bone
C. Inflammation of the bone
D. defective mineralization of the skeletal matrix

Answer 31

D. A defective mineralization of the skeletal matrix