Chapter 10 Endocrine System Flashcards
Endocrine System
glands secrete hormones
Glands are ductless
Hormones exert specific effects on target organs
Amines
structural variation of amino acid tyrosine
includes Thyroxine, epinephrine and norepinephrine
Proteins
Chain of 50-200 amino acids
includes insulin, growth hormone and calcitonin
Steroids
Cholesterol is the precursor
includes cortisol, aldosterone, estrogen, testosterone, and progesterone
Regulation of hormone secretion
negative feedback back mechanism- info about hormone effects are fed back to the gland
The pituitary gland
two major portions is: posterior pituitary gland and the anterior pituitary gland
What are the hormones in Posterior Pituitary Gland?
2 hormones: antidiuretic and oxytocin
Antidiuretic Hormone (ADH or vasopressin)
Function:
•Increases water reabsorption by the kidney tubules (water returns to the blood)
•decreases sweating
•causes vasoconstriction (in large amounts)
Regulation: Decreased water in content in the body
Oxytocin
Functions:
•Promotes contraction of myometrium of uterus (labor)
•promotes release of milk from mammary glands
Regulation:
•Nerve impulses from hypothalamus the result of stretching of cervix or stimulation of nipple
•secretion from placenta at end of gestation-stimulus unknown
What are the hormones of the anterior pituitary gland?
Growth hormone
thyroid stimulating hormone
adrenocorticotropic hormone
prolactin
follicle-stimulating hormone
luteinizing hormone
Growth Hormone
Function:
•Increases rate for mitosis
•increases amino acid transport into cells
•increases rate of protein synthesis
•increases use of fats for energy
Regulation of secretion:
GHRH (hypothalamus) stimulates secretion
GHIH-somatostatin (hypothalamus) inhibits secretion
Thyroid-stimulating (TSH)
Function:
•Increases secretion of thyroxine and T3 by thyroid gland
Regulation of secretion:
TRH (hypothalamus)
Adrenocorticotrophic hormone (ACTH)
Function:
•Increases secretion of cortisol by the adrenal cortex
Regulation of secretion:
CRH (Hypothalamus)
Prolactin
Function:
•Stimulates milk production by the mammary glands
Regulation of secretion:
•PRH (hypothalamus) stimulates secretion
•PIH (hypothalamus) inhibits secretion
Follicle-Stimulating hormone (FSH)
Function:
In women-
• Initiates growth of ova in ovarian follicles
• Increases secretion of estrogen by follicle cells
In men-
• Initiates sperm production in the testes
Regulation:
•GNRH (hypothalamus) stimulus secretion
•Inhibin (ovaries or testes) inhibits secretion