Chap-17 Porphyria Flashcards
1
Q
Mitochondrial disorder p.
A
- ALA-synthase
- Heridatary copro-P.
- Variegate P.
- Erythropoeitic Proto.P
2
Q
Cytoplasmic disorder p.
A
- ALA dehydrates def P.
- A.I.P
- Cong. Erythropoeitci P.
- P.Cutanae tarda
3
Q
ALA synthase:
A
Succinyl co-A + Glycine —> ALA
4
Q
ALA-dehydratase
A
ALA–> PBG
ALA dehy-deff
5
Q
PBG deaminase
A
PBG –> OH’methylbilane (HMB)
A.I.P
6
Q
URO-Gen 3 synthase
A
Oh’Methylbilane(HMB) –> Urogen III
Cong erythropoeitic P.
7
Q
URO-GenIII-decarboxylase
A
Urogen3–>Copro III
P.Cutanea tarda
8
Q
COPRO.III-Oxid
A
CoproIII–> Protogen9
Heridatary copro.P
9
Q
Protogen.oxid
A
Protogen9–> Proto 9
variegate.P
10
Q
Ferrechelotase
A
Proto-9—>Heme
Erythropoeitic proto.P