Chap 10 Quiz Flashcards

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1
Q

The two locations of triacylglycerol digestion

A

Mouth and Stomach

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2
Q

The lipase for mouth and stomach

A

Mouth - lingual lipase

Stomach - gastric lipase

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3
Q

Both lipases for triacylglycerol digestion are active at

A

low pH

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4
Q

Triacylglycerol Digestion does not require

A

other proteins cofactors for max. activity

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5
Q

Synthesis of Triacylglycerols occurs predominantly in

A

enterocytes

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6
Q

Lipoproteins defined

A

Spherical micelles of phospholipids and apolipoproteins surrounding a neutral lipid core

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7
Q

Examples of Lipoproteins

A

HDL
IDL
LDL
VLDL

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8
Q

Structure of a Lipoprotein

A

Triglyceride and cholesteryl ester core

Phospholipid and cholesterol coat

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9
Q

Three mechanisms in which lipids enter the cell

A

Diffusion

Transport

Receptor-mediated endocytosis

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10
Q

Receptor-mediated endocytosis defined

A

Process in which the cell internalizes particles and uses the cholesterol contents of low-density lipoproteins

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11
Q

What binds to the receptor in receptor-mediated endocytosis

A

Ligand (clathrin)

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12
Q

Triacylglycerol Synthesis occurs where

A

liver and adipose tissue

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13
Q

Triacylglycerol Synthesis in the liver

A

de novo synthesis from actyl-CoA

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14
Q

Triacylglycerol Synthesis in adipose tissue

A

Re-esterifies free fatty acids (storage)

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15
Q

Enzymes for triacylglycerol synthesis are found in

A

the endoplasmic reticulum

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16
Q

In digestion lipids are emulsified by

A

bile salts into smaller droplets

17
Q

Pancreatic lipase hydrolyzes

A

ester bonds in triacylglycerols releasing fatty acids

18
Q

Triacylglycerols are packaged into what form to travel the blood stream

A

chylomicrons

19
Q

Lipoprotein are complex particles composed of

A

Lipids (cholesterol/triglycerides) & Proteins

20
Q

Chylomicrons are the

A

largest and least dense lipoproteins and are primarily transporting dietary triglycerides from intestine to tissue

21
Q

HDL are synthesized in the ____ and involved in _____

A

liver; reverse cholesterol transport for excretion

22
Q

Diffusion is a _____ process for lipoproteins

A

passive; moves from areas of high concen. to lower

23
Q

Transport involves specific

A

carrier proteins embedded in cell membranes

24
Q

Receptor-Mediated Endocytosis specific process involving

A

the binding of extracellular ligands

25
Q

Reverse Cholesterol transport defined

A

Removal of cholesterol from the circulation and peripheral tissue to the liver

26
Q

Enzyme that catalyzes the dephosphorylation of phosphatidate to diacylglycerol

A

Lipin

27
Q

Lipid Storage droplets defined

A

The organelle that stores neutral lipids in the cells

28
Q

Lipolysis Defined

A

The regulated mobilization and breakdown of triacylglycerols

29
Q

**Lipolysis defined (extra)

A

triggered by hormone signaling

Occurs at low background levels

Regulated by AMP kinase

30
Q

Types of triacylglycerol storage

A

Acute and chronic

31
Q

Acute storage

A

+ Mobilization occurs over minutes to hours

+cAMP is manipulated via hormones and cell signaling cascades

32
Q

Chronic storage

A

+ Occurs over weeks or longer

+ Partially affected by both levels of gene expression and diet