Ch. 51 Flashcards
Causes of acute diarrhea
Bacterial Viral Drug induced Nutritional factors Protozoa
Causes of chronic diarrhea
tumors DM Addisons Disease Hyperthyroidism IBS AIDS
MOA: coat the walls of the GI tract, binding the causative bacteria or toxin, which is then eliminated through the feces.
adsorbents
bismuth subsalicylate
adsorbents
kaolin-pectin
adsorbents
activated charcoal
adsorbents
attapulgite
adsorbents
MOA: decrease intestinal muscle tone and peristalsis of the GI tract.
Anticholinergic (Antimotility)
belladonna alkaloids
Anticholinergic (Antimotility)
atropine
Anticholinergic (Antimotility)
hyoscyamine
Anticholinergic (Antimotility)
MOA: decrease intestinal motility and relieve rectal spams.
Opioid (Antimotility)
paregoric
Opioid (Antimotility)
pium tincture
Opioid (Antimotility)
codeine
Opioid (Antimotility)
loperamide
Opioid (Antimotility)
diphenoxylate
Opioid (Antimotility)
Supply missing bacteria to the GI tract, suppressing the growth of diarhhea-causing bacteria
Intestinal flora modifiers
L. acidophilus
Intestinal flora modifier
Adverse Effects: Increased bleeding time, constipation, dark feces, confusion, twitching, hearing loss, tinnitus, metallic taste, blue
gums
Adsorbents
Adverse Effects: Urinary retention, hesitancy, impotence, headache, dizziness, confusion, anxiety, drowsiness, dry skin, rash, flushing, blurred vision, photophobia, increased intraocular
pressure
Hypotension, hypertension, bradycardia, tachycardia
Anticholenergics
Adverse Effects: Drowsiness, sedation, dizziness, lethargy, nausea, vomiting, anorexia, constipation, respiratory depression, hypotension, urinary retention, flushing
Opiates
MOA: High fiber, absorb water to increase bulk, distend intestines to initiate reflex intestinal activity
Bulk Forming Laxatives
psyllium
Bulk Forming Laxatives
methylcellulose
Bulk Forming Laxatives
MOA: Stool softeners and lubricants. Promote more water and fat in the feces. Lubricate the fecal material and intestinal walls
Emollient laxatives
docusate salts
Emollient (fecal softeners)
mineral oil
Emollient (lubricant)
MOA: Increase fecal water content. Result: bowel distention, increased peristalsis, and
evacuation
Hyperosmotic laxatives