Ch. 5 Using Drugs Therapeutically Flashcards
receptors
protein molecules located on the cell membranes of every cell
agonist drug
a drug that is able to unlock and activate a receptor and produce an effect
ex: a key unlocks and activates the receptor
antagonist drug
AKA blocker drugs
drugs binding to a receptor, but cannot actually unlock and activate the receptor to produce an effect
ex: a key that blocks receptor but cannot activate
pharmacodynamics
the mechanism of action by which drugs produce their effects (desire or undesired), based on time and dose
pharmaotherapy
the knowledge and use of drugs to produce a therapeutic effect in the body
local drug effect
limited to the site of administration and to those tissues immediately surrounding the site
systemic drug effect
one that is felt throughout the body; drugs taken orally
therapeutic effect
main reason for which the drug was prescribed by the physician or other healthcare provider. it’s intended to prevent disease, to diagnose a disease, or to treat disease by preventing, controlling, improving, or curing the symptoms of the disease. towards specific area of body.
side effects
drug effects other than the therapeutic effect. it can mild and temporary, moderate and annoying, or severe enough that the patient must stop taking the drug.
adverse effect/adverse drug reaction (ADR)
a severe side effect.
recorded during the clinical trials of a drug.
toxic effect
results when the blood level of a drug rises above the the therapeutic level to a higher level that is toxic
paradoxical effect
one in which a drug that normally produces a specific therapeutic effect actually produces the opposite effect in certain patients.
allergic reaction
type of side effect, but one that has a seopcific underlying cause: the release of histamine that occurs even when a drug is a therapeutic level.
occurs when body’s immune system identifies a foreign substance (antigen) and send antibodies to combine with the foreign substance.
anaphylaxis or anaphylactic shock
a drug can cause any degree of an allergic reaction in a hypersensitive person. most severe symptom.
pharmacogenetics
the study of how the genetic makeup of different people affects their response to certain drugs.
idiosyncratic reaction
not a side effect and is not an allergic reaction. its an individual’s unique reaction to a drug, and it differs from side effects commonly associated with that drug
ex: malignant hyperthermia (uncontrolled elevated body temperature)
polypharmacy
patients taking more than one drug on a daily basis
synergism
when two drugs interact to produce an effect that is greater than the independent effect of each drug.
beneficial or undesirable
antagonism
another type of drug-drug interaction.
occurs when two drugs combine to produce an effect that is less than the intended effect for either drug
noncompliance
condition in which the patient is unwilling or unable to comply with taking a drug in accordance witht he prescribed dose or frequency
Abbreviation
a.c. ad lib. b.i.d. -c h.s p.c. p.r.n. q.d. q.h. q.h.s. q.i.d. q.o.d. -s t.i.d
Latin Phrase Medical Meaning
ante cibum - before meals
ad libitum - as needed
bis in die - twice a day
cum - with
hora somni - at bedtime (hour of sleep)
post cibum - after meals
pro re nata - as needed
quaque die - every day
quaque hora - every hour
quaque hora somni - at bedtime (hour of sleep)
quater in die - four times aday
(informal usage) - every other day
sine - without
ter in dies - three times a day