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Pharmacology > Ch. 20 Analgesic Drugs > Flashcards

Ch. 20 Analgesic Drugs Flashcards

1
Q

Salicylate Analgesic

A 
over-the-counter drugs.
3 therapeutic effects: 
Analgesic
Anti-Inflammatory
Antipyrectic
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2
Q

Salicylate Drug List

A

aspirin (Bayer Aspirin, Ecotrin, Empirin)
diflunisal
magnesium salicylate (Doan’s)
salsalate (Salsitab)

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3
Q

Analgesic

A

provide relief from mild-to-moderate pain by inhibiting the release of prostaglandins from damaged tissue

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4
Q

Anti-Inflammatory

A

Decrease inflammation, also by inhibiting the release of prostaglandins from damaged tissue

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5
Q

Antipyrectic

A

reduce fever by acting on the hypothalamus to cause vasodilation and sweating. This increases heat loss from the skin and lowers an elevated body temperature.

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6
Q

Anticoagulant

(4th therapeutic effect that is unique and not shared by other salicylate drugs

A

Aspirin prolongs the clotting time of the blood by inhibiting thromboxane, a substance in blood that causes platelets to aggregate.

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7
Q

Nonsalicylate Analgesic

A

include acetaminophen and other drugs that relieve pain with a therapeutic effect that is different from that of the salicylate drug aspirin.

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8
Q

Acetaminophen

Tylenol

A

nonsalicylate drug that is not related to aspirin.
2 therapeutic effects;:
Analgesic - weakens enzyme COX-1 and COX-2
Antipyretic

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9
Q

Nonsalicylate Drug List

A

acetaminophen
clonidine (Duraclon)
zinconotide (Prialt)

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10
Q

Nonsteroidal Anti-Inflammatory Drug

NSAIDs

A

have an analgesic effect because they inhibit the production of prostaglandins.
treat mild-to-moderate pain and inflammation
Subcategory of COX-2 inhibitor drugs

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11
Q

NSAIDs List

A 
celecoxib (Celebrex)
diclofenac
etodolac
fenoprofen (Nalfon)
ibuprofen (Advil, Motrin IB)
indomethacin (Indocin)
ketoprofen
ketorolac
meclofenamate
mefenamic acid (Ponstel)
meloxicam (Mobic)
naproxen (Aleve,Anaprox, Naprosyn)
oxaprozin (Daypro)
piroxicam (Feldene)
sulindac (Clinoril)
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12
Q
  • profen

- coxib

A
  • common to generic NAIDs

- common to generic COX-2 inhibitor drugs

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13
Q

esomeprzaole (Nexium)

lansoprazole (Prevacid)

A

proton inhibitor drugs decrease the amount of acid in the stomach and are used to treat ulcers caused by NSAIDs

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14
Q

Narcotic Analgesic Drugs

A

used to treat moderate-to-severe pain.
Narcotic means numbness. also produce sedation and a sense of heightened well-being (euphoria)
relieve pain by binding to opioid receptors in the brain and blocking pain impulses coming from nerves in the body

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15
Q

Narcotic Analgesic List

A 
buprenorphine (Butrans)
butorphanol (Stadol)
codeine
fentanyl (Abstral, Actiq, Duragesic, Fentora, Onsolis)
hyrdocodone (Zohydro ER)
hydromorphone (Dilaudid)
levorphanol (Levo-Dromoran)
meperidine (Demerol)
methadone (Dolophine, Methadose)
morphine (Astramorph, Duramorph, MS Contin)
nalbuphine (Nubain)
oxycodone (Oxecta, OxyContin)
oxymorphone (Opana)
pentazocine (Talwin)
tapentadol (Nucynta)
tramadol (Ultram)
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16
Q

Percodan (aspirin,oxycodone)

A

Schedule II, III drugs.

17
Q

Vicodin (acetaminophen, hydrocodone)

A

Schedule II,III,IV, V drugs

18
Q

Migraine Headache

A

a specific type of headache that has a sudden onset with severe, throbbing pain, often on just one side of head.
caused by a constriction of the arteries in the brain followed by a sudden dilation.

19
Q

Serotinin Receptor Agonist Drug

antimigraine agents

A

a neurotransmitter that normally constricts the arteries in the brain

20
Q

Serotinin Drug List

A 
almotriptan (Axert)
eletriptan (Relpax)
frovatriptan (Frova)
naratriptan (Amerge)
rizatriptan (Maxalt)
sumatriptan (Imitrex)
zolmitriptan (Zomig)
21
Q

-triptan

A

common to generic serotonin receptor agonist drugs

22
Q

Ergotamine Drugs

antimigraine agents

A

constrict the arteries in the brain without significantly reducing blood flow.

23
Q

Ergotamine Drug List

A

dihydroergotamine (Migranal)

ergotamine (Ergomar)

24
Q

Beta-Blocker Drugs

A

block the effect of epinephrine and keep the arteries in the brain dilated to prevent the initial vasoconstriction that begins a migraine headache

25
Q

Beta-Blocker Drug List

A 
atenolol (Tenormin)
metoprolol (Lopressor, Toprol)
nadolol (Corgard)
propranolol (Inderal)
timolol (Blocadren)
26
Q

Calcium Channel Blocker Drug

A

block the movement of calcium ions through calcium channels in the cell membranes of smooth muscle around the arteries in the brain.

27
Q

Calcium Channel Blocker Drug List

A

diltiazem (Cardizem)

verapamil (Calan, Covera-HS)

28
Q

Antidepressant Drug List

A 
amitrptyline
doxepin (Sinequan)
fluvoxamine (Luvox)
imipramine (TRofranil)
trazodone (Oleptro)
29
Q

Acute pain

A

sudden and severe

30
Q

Chronic pain

A

continuing for three months or longer

31
Q

opiate drugs

A

drugs made from natural opium poppy plant

32
Q

opioid drugs

A

made synthetically

Pharmacology (11 decks)

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