Ch. 5 - Membrane and Transport Learning Flashcards
half of a phospholipid bilayer
Leaflet
one or more regions that are physically embedded in the hydrophobic interior; stretches of non-polar amino acids that span the membrane from one leaflet to the other
Transmembrane Proteins
lipid molecule that is covalently attached to an amino acid side chain within the protein; integral membrane proteins
Lipid-Anchored
no interaction with the hydrophobic interior; bound to regions of integral membrane proteins that project out from the membrane and/or they are bound to the polar head groups of phospholipids
Peripheral Membrane Proteins
movement of membrane components occurs only in two dimensions
semifluid
group of lipids that float together as a unit within a larger sea of lipids
lipid raft
two fatty acids, one glycerol molecule, one phosphate, and a polar head group
phospholipid
extract a lipid from one membrane, diffuse through cell, & insert the lipid into another membrane
Lipid Exchange Proteins
process of covalently attaching a carbohydrate to a lipid or protein
Glycosylation
attachment of a carbohydrate to the amino acid asparagine in a polypeptide; attached to nitrogen atom
N-linked
addition of string of sugars to the O atom of a serine or threonine side chain in a polypeptide
O-linked
the movement of ions & molecules across biological membranes
Membrane Transport
allowing the passage of some ions & molecules but not others
Selective Permeability
when a substance moves across a membrane from an area of high concentration to one of lower concentration by passing directly through the phospholipid bilayer
Simple Diffusion
when a transport protein provides a passageway for a substance to cross a membrane from an area of high concentration to one of lower concentration
Facilitated Diffusion
moves a substance from an area of low concentration to one of high concentration with the aid of a transmembrane protein
Active Transport
the concentration of a solute is higher on one side of the membrane than on the other
Concentration Gradient
dual gradient with both electrical and chemical compounds
Electrochemical Gradient
concentration on both sides are equal
Isotonic
when the concentration of solutes outside of the cell is higher
Hypertonic
lower concentration of solutes than the opposite side
Hypotonic
water moves across the membrane from the hypotonic into the hypertonic; moving down the concentration gradient
Osmosis
when a cell takes up too much water and ruptures
Osmotic Lysis
when water leaves the cell and the cell shrinks
Crenation
if the extracellular fluid surrounding a plant cell is hypertonic, water will exit the cell and the plasma membrane will pull away from the cell wall
Plasmolysis
transmembrane proteins that forms an open passageway for the facilitated diffusion of ions or molecules across the membrane
Channel Transmembrane Proteins
open to allow the diffusion of solutes and close to prohibit diffusion; controlled by ligands
Gated Transmembrane Proteins
bind one or more solutes in a hydrophilic pocket and undergo a conformational change that switches the exposure of the pocket from one side of the membrane to the other side
Transporters
bind one ion or molecule & transport it across the membrane
Uniporters
bind two or more ions or molecules and transport them in the same direction
Symporters
bind two or more ions or molecules and transport them in opposite directions
Antiporters
functioning of a pump
Primary Active Transport
a type of transporter that directly uses energy to transport a solute against a concentration gradient
pump
pre-existing gradient drives the active transport of another solute
Secondary Active Transport
actively transports Na+ & K+ against their gradients by using the energy from ATP hydrolysis
Na+/K+ - ATPase
material inside the cell is packaged into vesicles and then excreted into the extracellular membrane
Exocytosis
plasma membrane folds inward to form a vesicle that brings substances or particles into the cell
Endocytosis
a receptor in the plasma membrane is specific for a given cargo
Receptor-Mediated Endocytosis
formation of membrane vesicles from the plasma membrane as a way for cells to internalize the extracellular fluid
Pinocytosis
formation of an enormous membrane vesicle which engulfs a large particle such as a bacterium
Phagocytosis