Ch 49 Drugs to Treat Anemias Flashcards

1
Q

What is plasma?

A

the liquid part of blood; contains proteins essential for the immune response and blood clotting

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2
Q

Leukocytes

A

WBC - part of the immune system

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3
Q

Erythrocytes

A

RBC - carry oxygen to the tissues and remove carbon dioxide

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4
Q

Why is iron needed to make healthy RBC?

A

iron helps to form hemoglobin rings to carry the oxygen

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5
Q

Why is vitamin B12 and Folic Acid needed to make healthy RBC?

A

to form a supporting structure that can survive being battered through blood vessels for 120 days

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6
Q

Why are amino acids and carbohydrates needed to make health RBC?

A

to complete the hemoglobin rings, cell membrane, and basic structure

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7
Q

What are the types of anemias?

A

Iron Deficiency Anemia, Megaloblastic Anemia, Sickle Cell Anemia

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8
Q

When is folic acid the most important?

A

most important in pregnancy, prevents defects in fetus, a deficiency can cause stillbirth

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9
Q

When is the ideal time for a women to begin supplementing vitamin B12 when planning for a family?

A

3-6 months before pregnancy

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10
Q

What group does Sickle Cell anemia affect?

A

African Americans

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11
Q

Who is at risk for Iron Deficiency Anemia?

A

menstruating women, pregnant and nursing women, rapidly growing adolescents, person with GI bleed

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12
Q

Who is at risk for Megaloblastic Anemia (Folic Acid)?

A

secondary to increased demand, absorption problems in the small intestine, drugs that cause folate deficiencies, secondary to the malnutrition of alcoholism

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13
Q

Who is at risk for Megaloblastic Anemia (Vitamin b12) ?

A

poor diet or increased demand
lack of intrinsic factor in the stomach

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14
Q

What is the medication ending for Erythropoiesis -Stimulating Agents?

A

poetin

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15
Q

What are examples of medication of Erythropoiesis -Stimulating Agents?

A

Epoetin Alfa (Epogen, Procrit)

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16
Q

What is the route for Erythropoiesis -Stimulating Agents?

A

subcutaneous; given in the abdomen

17
Q

what is the action of Erythropoiesis -Stimulating Agents?

A

stimulate bone marrow to make more red blood cells

18
Q

what are Erythropoiesis -Stimulating Agents used for?

A

Anemia associated with renal failure and AIDS

19
Q

What are the adverse affects of Erythropoiesis -Stimulating Agents?

A

hypertension
headache
dizziness
weakness
GI upset

20
Q

What should a nurse consider when giving Erythropoiesis -Stimulating Agents?

A

do not use if a patient has uncontrolled hypertension
do not give if patient has allergy to human albumin
check hemoglobin, hematocrit, and platelet values

21
Q

What is a medication example of Iron Deficiency Anemia Agents?

A

Ferrous Sulfate (Feratab)
Iron Sucrose (Venofer)

22
Q

What is the route of Iron Deficiency Anemia Agents?

A

PO/IV

23
Q

What is the action of Iron Deficiency Anemia Agents?

A

elevate serum Iron concentration

24
Q

What is Iron Deficiency Anemia Agents used for?

A

iron deficient anemia
adjunct treatment with Epoetin Alfa

25
Q

What are the adverse affects of Iron Deficiency Anemia Agents?

A

dark and tarry stools
CNS toxicity
anaphylactic reaction
GI Upset

26
Q

What should a nurse consider when giving Iron Deficiency Anemia Agents?

A

give 2 hours before of after antacids
do not give with calcium containing foods
check iron, hemoglobin, hematocrit, and platelet values
this is not for hemolytic anemia

27
Q

What is the antidote for Iron Deficiency Anemia Agents?

A

Deferoxamine Mesylate (Desferal)

28
Q

What is medication examples for Agents for Megaloblastic Anemia?

A

Folic Acid (Folate)
Cyanocobalamin (Vitamin B12)

29
Q

What is the route for Agents for Megaloblastic Anemia?

A

Oral, Nasal Spray, SQ, IM, IV

30
Q

What is the action of Agents for Megaloblastic Anemia?

A

essential for production of strong stoma in RBC’s
maintenance myelin sheath nerve tissues

31
Q

what is Agents for Megaloblastic Anemia used for?

A

replacement therapy for dietary deficient megaloblastic anemia

32
Q

what are the adverse effects of Agents for Megaloblastic Anemia?

A

irritation at injection site, nasal irritation, GI upset

33
Q

What should a nurse consider when giving Agents for Megaloblastic Anemia?

A

H&P, basic exam, CMP, BMP, CBC, pregnancy and lactation

34
Q

What are medication examples of Agents for Sickle Cell Anemia?

A

Hydroxyurea (Hydrea, Droxia)

35
Q

What is the action of Agents for Sickle Cell Anemia?

A

increase dental hemoglobin produced in bone marrow
dilutes abnormal hemoglobin S

36
Q

what is the use for Agents for Sickle Cell Anemia?

A

replacement therapy for dietary deficient megaloblastic anemia

37
Q

what are the adverse effect of Agents for Sickle Cell Anemia?

A

increased cancer risk, disorientation, CNS effects, GI upset

38
Q

what should a nurse consider when giving Agents for Sickle Cell Anemia?

A

use cautiously in liver or renal impaired clients
do not give in severe anemia clients