Ch 43 Drugs Affecting Blood Pressure Flashcards
What determines blood pressure?
heart rate, stroke volume, total peripheral resistance
what are the factors that influence blood pressure?
baroreceptors and RAAS
What factors increase blood pressure?
psychological stress, exposure to high frequency noise, high salt diet, lack of rest, genetic predisposition
What happens when hypertension is left untreated?
CAD and cardiac death, stroke, renal failure, loss of vision
What are the hypertension risks leading to CAD?
heart muscle thickening, increased pressure generated by the muscle on contraction, increased workload
What causes hypotension?
the heart muscle is damaged and unable to pump efficiently, severe blood or fluid loss, extreme stress and the body’s levels of norepinephrine are depleted leaving the body unable to respond to stimuli to raise bp
What is the medication ending for ACE inhibitor
PRIL
How does an ACE inhibitor work?
blocks ACE from converting A1 to A2
What does an ACE inhibitor treat?
hypertension, congestive heart failure, DM Nephropathy
What are the adverse reactions of an ACE Inhibitor?
cough, hyperkalemia, angioedema
What should the nurse teach a patient taking an ACE inhibitor?
take on an empty stomach, NSAIDS reduce medication
what are the medication names of an ACE Inhibitor?
captopril (Capoten)
lisinopril (Zestril)
What is the medication ending of an Angiotensin II Receptor Blocker?
SARTAN
How does ARB work?
bind with A2 receptors to block vasoconstriction and aldosterone release
what does an ARB treat?
hypertension, DM Nephropathy
What are the adverse affect of an ARB?
hypotensive effects, GI sensitivity
What should the nurse consider when caring for a patient taking an ARB?
use cautiously with hepatic or renal dysfunction, ARB decreases effectiveness of Phenobarbital, Cardizem decreased ARB’s effectiveness
What are the ARB medications?
losartan (Cozaar)
candesartan (Atacand)