Ch 2: Fuel for Exercise: Quiz 1 Flashcards

1
Q

Bioenergetics

A

ATP Formation

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2
Q

Energy

A

the capacity to perform work

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3
Q

Laws of Thermodynamics

A
  1. Energy is never created or destroyed; it only changes from one form to another
  2. Entropy is always increasing in the universe
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4
Q

2nd Law of Thermodynamics

A
  • Everything tends to disorder. To reorder part of universe, we must put energy into it.
  • No system is 100% efficient. Some energy is lost as heat. Heat lost to outside not used productively. We can look at amount of heat produced as the inefficiency of the system.
  • We measure energy in the body as a measure of the amount of heat produced in the kilocalorie
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5
Q

1 kilocalorie

A

energy needed to raise the temperature of 1 kg of water from 14.5 to 15.5 C

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6
Q

Coupled Reactions

A
  • linked reactions, with energy made in one reaction being used to drive a second reaction
  • Oxidation-reductions (REDOX) reactions are an important type of coupled reaction
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7
Q

Energy transfer in the body

A
  • occurs via release of energy trapped within chemical bonds of various molecules
  • chemical bonds containing relatively large amounts of potential energy are often called “high energy” bonds
  • endergonic reactions
  • exergonic reactions
  • in body, energy is usually released in many small, controlled steps, as opposed to 1 single reaction
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8
Q

endergonic reactions

A

require energy be added to reactants

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9
Q

exergonic reactions

A

give off energy

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10
Q

Oxidation

A

removing an electron from an atom or molecule

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11
Q

Reduction

A

addition of an electron to an atom or molecule

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12
Q

REDOX

A

oxidation and reduction always coupled

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13
Q

Often, REDOX reactions involve the transfer of H+ atoms rather than free electrons.

A
  • hydrogen atom contains 1 electron, so an atom or molecule that loses a hydrogen atom loses an electron and is oxidized, the molecule that gains the hydrogen (and electron) is reduced.
  • two molecules play important roles in the transfer of hydrogens, NAD+ and FAD+. Reduced forms are NADH+, H+ and FADH2
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14
Q

Enzymes

A
  • speed up chemical reactions by lowering activation energy
  • “Lock and Key Mechanism”
  • not used up in reaction
  • enzyme activity measured by rate at which substrates converted to products (influenced by several factors, especially temperature and pH)
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15
Q

Catabolism

A

big molecule to small molecules

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16
Q

Anabolism

A

small molecules to big molecule

17
Q

Coenzyme

A
  • complex, non-protein, organic molecules that associate closely with an enzyme
  • an enzyme dependent on a coenzyme will not function optimally without enough coenzyme.
  • B vitamins and Mg+ are coenzymes for many enzymes of carbohydrate, fatty acid and amino acid metabolism
  • without coenzyme, metabolism slows
18
Q

carbohydrate

A
  • 1:2:1 ratio of C, H, & O
  • glucose
  • sucrose (disaccharide) [glucose + fructose]
  • polyssacharides
  • 4.1 kcal/g CHO
19
Q

polysaccharides

A
plant form
-cellulose (fiber)
-starch
animal form (glycogen)
-glucose polymer
-storage (muscles, liver)
-glycogenesis-glycogen synthase
-glycogenolysis-glycogen phosphorylase
20
Q

Fats (Lipids)

A
  • greater C/O ratio that CHO
  • large stores (store more fat than carbohydrate)
  • 9.4 kcal/g fat (most efficient fuel to use)
  • harder to activate (slowest/hardest to use)
  • prolonged, low intensity exercise
  • triglycerides
21
Q

triglycerides (storage fats)

A
  • 1 Glycerol + 3 Free Fatty Acids (FFAs)

- Lipolysis-lipases

22
Q

Saturated or Unsaturated fats are better? and Why?

A

Unsaturated fats are better because there is a smaller calorie content. Big health component-cell membrane,etc. More fluid

23
Q

Proteins

A
  • long chains of amino acids (aa’s)
  • must break into aa’s and remove N before using for energy (happens during urea cycle)
  • 2-3% of energy at rest
  • 5-10% in prolonged submax exercise
  • 4.1 kcal/g protein
24
Q

High Energy Phosphates

A

-ATP= 1 adenine + 1 ribose + 3P
-Making ATP requires much energy. We link exergonic reactions to endergonic ones to form ATP
-Synthesis (ADP + Pi + E–> ATP)
-Breakdown
(ATP —> ADP + Pi + E) By ATPase. Energy used to do bodily work

25
Q

Bioenergetics

A
  • Muscle cells store limited amounts of ATP
  • Metabolic Pathways produce ATP rapidly
  • Aerobic vs. Anaerobic
26
Q

Aerobic

A

requires oxygen

27
Q

Anaerobic

A

doesn’t require oxygen

28
Q

Basic Energy Systems

A
  1. ATP-PCr system
  2. Glycolytic System
  3. Oxidative System
29
Q

ATP-PCr System

A

“phosphagen system”
cytoplasm
anaerobic

30
Q

Glycolytic System

A

cytoplasm

anaerobic

31
Q

Oxidative System

A

aerobic

mitochondria

32
Q

Red Blood Cells

A

carries oxygen

anaerobic (no cytoplasm)

33
Q

ATP-PCr/Phosphagen System

A

Phosphocreatine (PCr)- high-energy molecule in muscle used to reform ATP

Sources: Food; red meat/meat. Fish (best source) Body manufactures creatine in liver and kidney

  • Anaerobic
  • Cytoplasm
  • Simplest (one reaction/one enzyme)
  • Quickest
  • Provides energy at onset of exercise and to sustain high intensity muscular activity for - 10 sec.

can’t make phosphocreatine until you are in recovery

34
Q

ATP-PCr System

A

limitation: muscle cells store only small amounts of PCr.

need ATP to form PCr

  • can’t do until recovery
  • 50-70% restored in 30 sec
  • Full recovery in 10-30 min.

creatine supplementation

  • quicker recovery
  • most studies show more work when exercise is repeated
35
Q

Control of ATP-PCr System Creatine Kinase (CK)

A

PCr breakdown catalyzed by CK

CK controls rate of ATP production

  • negative feedback system
  • when ATP levels decreases (ADP increases) CK activity increases
  • when ATP levels increase, CK activity decreases
36
Q

Glycolytic System

A
  • anaerobic
  • cytoplasm
  • ATP yield: 2 to 3 mol ATP/ 1 mol substrate
  • duration: 15 s to 2 min