Ch 18: Practical Application of Immunology Flashcards
Who is credited for performing the first vaccinations using cowpox inoculations to prevent smallpox?
Edward Jenner
What type of virus is measles virus?
- Paramyxovirus
- (-)stranded, unsegmented, enveloped
What are some potential complications of measles?
- Blindness
- Inflammation of the brain
- Pneumonia
- Death
What percentage of people who aren’t vaccinated will get infected with measles if directly exposed?
90%
What percentage of people need to be vaccinated in a community to prevent measles spread (herd immunity)
92%
How many cases of measles are there annually worldwide?
70 million
It is estimated that as many as ___% of people would need to be immune to disrupt the rapid transmission of SARS-CoV-2
94%
What class of vaccines contain living pathogens?
- Attenuated whole-agent vaccines
- Ex: MMR, oral polio (OPV)
What class of vaccines contain killed pathogens?
- Inactivated whole-agent vaccines
- Ex: inactivated polio (IPV)
What class of vaccines contain inactivated toxins?
- Toxoids
- Ex: Tetanus
What class of vaccines contain antigenic proteins or fractions?
- Subunit vaccines
- Ex: Acellular pertussis, recombinant HepB, SARS-CoV-2
What class of vaccines contain antigens that are linked to another immunogenic molecule?
- Conjugated vaccines
What vaccinations are recommended for persons aged 0-6 years? (11)
- HepB
- Rotavirus
- DPT
- Haemophilus influenzae b
- Pneucoccal
- Inactivated poliovirus
- Influenza
- MMR
- Varicella
- HepA
- Meningococcal
Which types of HPV cause 90% of genital warts cases?
HPV types 6 and 11
Which types of HPV cause 70% of cervical cancers?
HPV types 16 and 18