CH. 16 ENDOCRINE - CLASS NOTES Flashcards
What is the second controlling system of the body?
Endocrine system
Hormones are also called:
chemical messengers
Hormones control 5 processes
reproduction growth and development mobilization of body defences homeostasis regulation of metabolism
5 effects caused by hormones
changes in plasma membrane permeabilityprotein synthesisenzyme activation/inactivationmitosis stimulation
secretory activity
hormones are produced by _____ cells
specialized
cells secreted hormones into _______ fluid
extracellular
hormones are transferred to target sites by the _______
blood
hormones _______ the activity of other cells
regulate
3 main hormone classifications
- steroids - can go through cell membrane
- non-steroids
- prostaglandins
hormones affect only certain _____ or ______
tissues, organs
target cells must have specific protein ________
receptors
2 mechanisms in which hormones act:
- direct gene activation (steroid)
2. second-messenger system (non-steroid)
direct gene activation (steroid)
- can go through plasma membrane
- enter nucleus
- activate genes & DNA
- effects can take 45 minutes to days
second messenger system
- cannot pass through membrane
- uses a receptor protein- faster (seconds to minutes)
3 hormone stimuli
- hormonal
- humoral
- nerve impulses (sympathetic)
hormone levels in the blood are mostly maintained by __________ feedback
negative
what does hormonal stimuli mean & give example
hormone release stimulated by other hormones
- pituitary gland targets thyroid gland
what is humoral stimuli & give example
hormone release stimulated by body fluids & blood
- insulin is produced based on blood sugar
what is neural stimuli & give example
hormone release stimulated by nerve impulses- release of adrenaline
8 major endocrine organs
- pituitary gland & hypothalamus
- pineal gland
- thyroid gland
- parathyroid gland
- adrenal gland
- thymus gland
- pancreas
- gonads
this gland is the size of a pea
pituitary gland
hangs by a stalk and connected to the hypothalamus
pituitary gland
pituitary gland has 2 functional lobes
anterior pituitary - glandular tissue
posterior pituitary - nervous tissue
what gland is known as the “master endocrine gland”
pituitary gland
how many hormones does the anterior pituitary gland secrete
6
2 anterior pituitary hormones that affect non-endocrine targets:
- growth hormone
2. prolactin
4 anterior pituitary hormones that affect endocrine targets - called tropic hormones:
- thyroid-stimulating hormone
- adrenocorticotropic hormone (ACTH)
3 & 4. gonadtropic hormones (FSH & LH)
3 characteristics of anterior pituitary hormones:
- proteins
- second-messenger sytems
- mostly regulated by negative feedback
general metabolic hormone
GROWTH HORMONE
growth of skeletal muscles and long bones
GROWTH HORMONE
causes amino acids to build proteins
GROWTH HORMONE
causes fats to be broken down for energy
GROWTH HORMONE
spares glucose to maintain blood sugar homeostasis
GROWTH HORMONE
3 main kind of GROWTH HORMONE disorders
- pituitary dwarfism
- gigantism
- acromegaly
stimulates milk production following childbirth
PROLACTIN
regulates endocrine activity of the adrenal cortex
ADRENOCORTICOTROPIC (ACTH)
influences growth and activity of thyroid gland
THYROID-STIMULATING HORMONE (TSH)
2 gonadtropic hormones
- FSH
2. LH
stimulates follicle development in ovaries and development of sperm in testes
FSH
triggers ovulation of egg in females and production of testosterone
LH