Ch 11 Corticosteroids

Question 1

Steroids aka glucocorticoid/ corticosteroid

Answer 1

Agents that produce an anti-inflammatory response in the body

Question 2

Advair diskus/ HFA combination

Answer 2

Fluticasone propionate/salmeterol

Question 3

Symbicort combination

Answer 3

Budesonide/ formoterol funarate HFA

Question 4

Dulera combination

Answer 4

Mometasone furoate/ formoterol fumarate HFA

Question 5

Breo Ellipta combination

Answer 5

Fluticasone furoate/ vilanterol

Question 6

Adrenal cortical hormones ( produced by the adrenal cortex)

Answer 6

1.Glucocorticoids -used in pulmonary disease

2. Mineralocorticoids- regulate body water and sex hormones
3. Androgen ( male) and estrogen (female) characteristics

Question 7

Hypothalamic pituitary adrenal axis(HPA Axis)

Answer 7

Pathway for release and control of endogenous corticosteroids

Stimulation of hypothalamus causes impulses where it’s corticotropin-releasing factor (CRF) is released

Question 8

Diurnal steroid cycle

Answer 8

Production of body’s own glucocorticoids follows circadian rhythm

Question 9

In asthmatic patients what infiltrates the airway and releases inflammatory mediators

Answer 9

Mast cells, recruited eosinophils, lymphocytes or macrophages infiltrate the airway

Question 10

What is a hazard of steroid use

Answer 10

Suppression of HPA axis

Question 11

What is the most common side effect and how to prevent it

Answer 11

Oropharyngeal candidiasis (oral thrush)

What to do:
1. Use minimal dose
2. Use reservoir
3. Rinse mouth after

Question 12

What’s the use of steroids in asthma

Answer 12

ICD have not been traditionally considered useful during secure severe asthma episodes

Question 13

Endogenous

Answer 13

Inside or produced by body

Question 14

Exogenous

Answer 14

Outside or manufactured for the body