Ch. 1-3 Proteins Flashcards
Shape of proteins
Each has unique 3D shape
Polymer of amino acids
Proteins
How do proteins vary
Sequence of amino acids
Importance of proteins
Major components of cell parts
Provide support
Storage of amino acids
Types of proteins
Receptor proteins
Contractile proteins
Antibodies
Enzymes
Building block of proteins
How many are there
Amino acids
20
How do you classify proteins
Based on properties of side chain
Nonpolar
Hydrocarbon chains
No oxygen
CH
Polar
Oxygen present Sometimes sulfur No charge CH2 I / C \\ NH2 O
Polar charged acidic
Negative charge
Donate H+ to solution
CH2 - CH2 - C = O
\
O-
Polar charged basic
Positive charge
Gain H+ from solution
NH3+ at end
What is the protein confirmation
Unique 3D shape
Describe primary protein shape
Sequence of amino acids
Determined by genes
(Sequence of bases in DNA)
What are the two types of secondary protein conformation
Alpha helix that looks like a spiral
Beta pleated sheet
Describe the secondary protein shape
Regular repeated folding of peptide chain
What is the folding of the peptide chain in the secondary protein shape stabilized by
Hydrogen bonds
Describe the tertiary protein conformation
Globular proteins
Irregular contortion
Enzymes
How is the shape of the tertiary protein conformation stabilized
By hydrogen bonds, ionic bonds, hydrophobic interactions, disulfide bridges
Describe the quaternary protein conformation
Interaction of several polypeptides
Three or more tertiary put together
Example is collagen and hemoglobin
Purpose of hemoglobin
Number of polypeptide chains
Carries oxygen
4
What is collagen
The binding protein in skin
When a protein loses its shape and therefore its function
Denaturation
What causes denaturation
Heat
Changes in pH more acidic
Any environmental toxin
Radioactivity or UV
What does a peptide bond between two amino acids look like
O H
I I I
C - N