Ch. 1/11 Flashcards
Anatomy of skeletal muscles
Muscle fibers
Myofibrils
3 types of muscle tissues
Skeletal muscle: voluntary, skeleton
Smooth muscle: involuntary, hollow organs
Cardiac muscle: involuntary, heart
Review: which muscle tissue is voluntary?
Skeletal
TF: Skeletal muscle is entirely surrounded by endomysium
False
Epimysium
TF: The fascicles within skeletal muscle is surrounded by perimysium
True
SM: Consists of individual muscle cells (muscle fibers)
Fascicles
SM: Muscle fiber is surrounded by …
-consists of myofibrils divided into…
Endomysium
Sarcomeres
MF: Plasmalemma
Fuses with …
Conducts … …
Maintains … . … …
Tendon
Action potential
PH, transports nutrients
MF: Sarcoplasm: … Of muscle cell
Cytoplasm
MF: Unique features within sarcoplasm
Glycogen storage
Myoglobin
MF: Transverse tubules
Extension of …
Carries .. deep into …
Plasmalemma
Action potential ➡️ muscle fiber
MF: Stores Calcium
Sarcoplasmic reticulum (SR)
How many myofibrils per muscle fiber?
Hundreds to thousands
MS: Basic contractile element of skeletal muscle
Sarcomere
Sarcomere: Striped appearance/striations (4)
– A-bands: dark/blue stripes
– I-bands: light/pink stripes
– H-zone: middle of A-band
– M-line: middle of H-zone
Sarcomere: common boundary structure
A-disk
Sarcomere: Thin protein filament that shows up lighter under 🔬 (red)
Actin
Sarcomere: 3 proteins within Actin and their functions
– Actin: contains myosin-binding site
– Tropomyosin: covers active site at rest
– Troponin: anchored to actin, moves tropomyosin
TF: A-band contains only actin filaments
False
I-band
Actin filaments are anchored at …
Z-disk
Sarcomere: Thick filaments that show up darker under 🔬 (blue)
Myosin
TF: H-zone contains only myosin filaments
True
What band contains both protein filaments
A-band
Myosin’s globular heads protrude … from thick filaments and will interact w/… for contraction
360°
Actin filaments
Function of Titian
Stabilizes sarcomere
Centers myosin
Prevents stretching
Titin extends from … to …
Z-disk to M-band
Muscle fiber contraction starts with …
Nervous system
MFC: innervates muscle fibers and is the motor unit
α-Motor neurons
MFC: More operating motor units =
More contractile force
Events of Excitation-Contraction Coupling (6) ⭐️
- Action potential (AP) starts in brain
- AP arrives at axon terminal, releases acetylcholine (ACh)
- ACh crosses synapse, binds to ACh receptors on plasmalemma
- AP travels down plasmalemma, T-tubules
- Triggers Ca2+ release from sarcoplasmic reticulum (SR)
- Ca2+ enables actin-myosin contraction
Action potential arrives at ST from . … & causes mass release of Ca into sarcoplasm
T Tubule
TF: SR sensitive to chemical charge
False
Electrical
Ca2+ binds to … on thin filament to move …
Troponin
Tropomyosin
Cross-bridge
Myosin binds to actin,
allowing a contraction to occur
Sliding Filament theory
Myosin and actin filaments sliding past each other