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Ther 201 3rd Exam > Cephalosporins > Flashcards

Cephalosporins Flashcards

0
Q

T/F each succeeding generation is more effective against g negative bacteria and broader spectrum of activity

A

T, 4th gen has broadest spectrum

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1
Q

Cephalosporins not active against

A

L. monocytogenes

Enterococci

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2
Q

Cefazolin

A

1st gen

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3
Q

Cephalothin

A

1

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4
Q

Cephalexin

A

1

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5
Q

Cephradine

A

1

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6
Q

Cefadroxil

A

1

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7
Q

Cefaclor

A

2

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8
Q

Cefamandole

A

2

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9
Q

Cefonicid

A

2

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10
Q

Cefuroxime

A

2

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11
Q

Cefprozil

A

2

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12
Q

Loracarbef

A

2

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13
Q

Ceforanide

A

2

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14
Q

Cefixime

A

3

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15
Q

Moxalactam

A

3

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16
Q

Ceftriaxone

A

3

17
Q

Cefotaxime

A

3

18
Q

Cefepime

A

4

19
Q

Gram positive cocci

A

Pneumococci
Streptococci
Staphylococci

20
Q

Cross allergenicity more common compared to other generations

A

1st

21
Q

The only first gen cephalosporin still in use

A

Cefazolin

22
Q

2nd gen extension, organisms?

A 
Klebsiella
H. influenza
B. fragilis
M. catarrhalis
N. gonorrhea
N. meningitides
23
Q

2nd gen cephalosporin that can cross the BBB

A

Cefuroxime

24
Q

3rd gen with useful activity against P. aeruginosa

A

Ceftazidime

Cefoperazone

25
Q

Used as empirical therapy of sepsis of unknown cause in immunocompromised and immunocompetent patients

A

3rd gen cephalosporins

26
Q

Reduced effects against staph but same activity against strep

A

Ceftriaxone

27
Q

Iv/im cns and genitourinary infections
Bone and joint infections
Skin and soft tissue infections
Mild community acquired respiratory infections

A

Ceftriaxone

28
Q

Adverse effect: biliary sludge

A

Ceftriaxone

29
Q

Has longest half life among 3rd gen

A

Ceftriaxone

30
Q

Goo activity against P. aeruginosa

A

Cefepime

31
Q

LRTs
UTI
Skin and soft tissue infections
Intra abdominal infections

A

Cefepime

32
Q

Most stable against beta lactamases produced by gram negative bacteria

A

Cefepime

33
Q

Pref for nosocomial infections and those caused by enterobacteriaceae

A

Cefepime

34
Q

Ceftriaxone administration

A

IM

IV

35
Q

Cefepime admin

A

IV

36
Q

Cefuroxime admin

A

IV

Oral

37
Q

Cefazolin admin

A

IM

IV

38
Q 
Alternative for antistaph penicillin
Surgical and endocarditis prophylaxis
Bone and joint infections
Pharyngitis
Community acquired UTIs
A

Cefazolin

39
Q

Kidney failure

Hemolytic anemia are effects of

A

Cefazolin

40
Q

Community acq uti and rti
Bone and joint infections
Skin and soft tissue infections

A

Cefuroxime

Ther 201 3rd Exam (16 decks)

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