Antibacterials 3 Flashcards

0
Q

Wide spectrum good activity
Gram neg rods
Gram pos organisms
Anaerobes

A

Imipinem

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1
Q

Most broad spectrum so is used for polymicrobial infections

A

Carbapenems

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2
Q

Imipenem most commonly administered with inhibitor of renal dehydropeptidase

A

Cilastatin

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3
Q

Carbapenem with longest halflife

A

Ertapenem

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4
Q

Carbapenems no effect on

A
MRSA
E faecium
C difficile
B cepacia
S maltophilia
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5
Q

Carbapenems not active against

A

L monocytogenes

Enterococcus

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6
Q

Excessive levels of imipenem in patients with renal failure may lead to

A

Seizures

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7
Q

Carbapenems Cross allergenicity with

A

Penicillin

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8
Q

Beta lactamase inhibitors

A

Clavulanic acid
Sulbactam
Tazobactam

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9
Q

B lactamase inhibitors have their own antibacterial activity, t or f

A

False

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10
Q

Tazobactam especially acts on which B lactamases

A

SHV-1

TEM

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11
Q

Diarrhea
Hepatitis, jaundice
Hemolytic anemia

A

Tazobactam

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12
Q

Tazobactam used in combination with

A

Piperacillin

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