Cells and Tissues: Epithelial Tissue Flashcards
key functions of epithelial tissues
Selective barriers
secretory
protection
Tight junctions
Claudins and occlaudins attach adjacent cells, maintain cell polarity, make cells electrically tight i.e. skin
Adherns Junctions
‘Belt desmosomes’, have a plaque layer joining actin (microfilament) to cadherins, catenins link the two, prevent from tension forces i.e. contractions
Desmosome
Have plaque, keratin spans from one side desmosome to another across cytoplasm to maintain shape and stick cells together, cadherin links intercellular space, i.e. muscle cells
Gap junctions
Direct channel between cells to pass messages, 6 connexIn’s form a connexOn, 2 gap juncs form a hemi channel, allow ~1kDa molecules i.e. cardiac tissue
junctional complex
tight, adherens, desmosome
microfilaments
ACTIN, bundles below membrane and cytoplasm,, strength, alter cell shape, tie cells together, muscle contraction
Intermediate Filaments
KERATIN, strength, move materials through cytoplasm
Hemidesmosome
Connect to the basement membrane, Intergrin links to laminin in the basement membrane and to Keratin intermediate filament
Basal Lamina
secreted by epithelial cells, contains collagen, laminin, other proteoglycans, glycoproteins etc is a TOP
reticular lamina
Produced by cells of underlying connective tissue fibroblasts, contains fiberous proteins fibroectin, collagen etc is a BOTTOM
Epithelia contain nerves but not blood vessels making them?
Avascular
How do epithelia recieve nutrients and remove waste
diffusion from vessels in connective tissue
4 functions of basement membrane
supports overlying epithelium, surface for cells migrate during growth and wound healing, a physical barrier, filtrates substances in the kidney
where is Covering and lining epithelia
form outer covering of skin and organs, inner lining of blood vessels, ducts and body cavities