Cell survival and Anemias

Question 1

Anemia in men

Answer 1

Less than 13.5 g/dL

Question 2

Anemia in women

Answer 2

Less than 12 g/dL

Question 3

Oxygen dissociation curve, shift left

Answer 3

“Likes oxygen” increased pH, decreased P50, temperature and 2,3 DPG

Question 4

oxygen dissociation curve shift right

Answer 4

” releases oxygen” decreased pH, increased p50 temperature and 2,3 DPG

Question 5

Aplastic Anemia

Answer 5

Bone marrow failure- cellular depletion with fatty deposit replacement

Question 6

Fanconi anemia

Answer 6

1 INHERITED cause of aplastic anemia. Different from fanconi syndrome (renal issues)

Question 7

Treatment for Aplastic Anemia

Answer 7

ATG (anti-thymocyte globulin) used to affect the immune cells that are targeting the bone marrow for removal, immuno-suppressents (cyclosporin) also depresses immune cells activity, get rid of toxins, HPC, supportive transfusions

Question 8

Impaired production anemias

Answer 8

Aplastic, Iron deficiency, megaloblastic and anemia of chronic disease

Question 9

Increased destruction anemias

Answer 9

PCH, PNH, TMA, mechanical heart vales, snake venoms, increased destruction in RES

Question 10

stored iron

Answer 10

ferritin

Question 11

iron transporter

Answer 11

transferrin

Question 12

megaloblastic anemia

Answer 12

folate deficiency, B12 deficiency (most commonly due to pernicious anemia)