Cell Membranes Flashcards
Name 3 roles of membranes within and at the surface of cells?
Act as a partially permeable barrier between the cell and its environment and also between organelles and the cytoplasm within organelles
Site of chemical reactions
Site of cell communication
What is the structure and function of the phospholipid bilayer?
Hydrophilic phosphate heads on outside, hydrophobic tails on inside
Central hydrophobic section doesn’t allow water soluble substances to pass through easily = barrier
What is the structure and function of cholesterol?
Cholesterol is a lipid with hydrophobic and hydrophilic end
Binds in between phospholipids (to tails) so they’re closer together making the membrane more fluid and stronger
What is the structure and function of glycolipids?
Lipid on membrane with carbohydrate chain attached
Stabilise membrane by forming h bonds with surrounding water
Receptors where drugs hormones and antibodies bind
Receptors in cell signalling
Antigens- recognise as self
What is the structure and function of a glycoproteins?
And extrinsic protein with carbohydrate chain attached
For cohesion of cells
Receptors for cell signalling
Receptors for drugs hornmones and antibodies
What do proteins do in the cell membrane?
Intrinsic proteins - channel and carrier proteins transport molecules across the membrane
Extrinsic proteins - on one side of the bilateral
What is the effect of temperature on membrane permeability?
Phospholipids gain kinetic energy = move more
This increases fluidity of membrane and it loses structure
= increase permeability
Channel and carrier proteins denature
- increases permeability
What is the effect of solvents on membrane permeability?
Organic solvents can dissolve the lipids in membranes as they are less polar than water
= more permeability
How can you investigate membrane permeability?
Using betroot
More pigment released = higher permeability
Higher absorbency on colorimeter
Define diffusion
The net movement of particles from an area of high concentration to an area of lower concentration
What is facilitated diffusion?
Diffusion across a methane through channel protein (polar substances as inside of Chanel proteins are polar)
Define active transport
The movement of molecules from an area of low concentration to high concentration requiring energy ATP
Using carrier proteins
- A molecule or ion binds to a _______ in a protein on the cell membrane
- Inside the cell _____ binds to the carrier protein and is hydrolysed to __________ and ____
- ______ binds to the carrier protein and changes it’s ________
- Molecule is _______ into cell
- ________ released and recombined with _____ to make _____
- Carrier protein returns to original state
Receptor Phosphate ADP Phosphate Shape Released Phosphate ADP ATP
Describe endocytosis
Phagocytosis (solids) or pinocytosis(liquids)
Membrane invaginates
Membrane enfolds material until it fuses to form a vesicle
Vesicle pinches off and moves to cytoplasm
Describe exocytosis
Vesicles formed at the Golgi
Vesicles move to and fuse with cell surface membrane
Contents released outside cell