Cell membrane & Transportation Flashcards

1
Q

What are the functions of the cell membrane?

A

Separates cell from the outside environment
Provide structure and protection
Gatekeeper-Controls substances entering and leaving the cell

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2
Q

What does Fluid Mosaic model mean?

A

a mosaic of protein molecules bobbing in a fluid bi-layer of phospholipids

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3
Q

What are the components of a cell membrane?

A
phospholipid bilayer
proteins
carbohydrates
Glycolipids
Glycoproteins
Cholesterol
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4
Q

What do proteins do in the cell membrane?

A

Determine membrane function
transmit chemical signals into the cell
act as carriers for specific substances

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5
Q

What do the carbohydrates do in the cell membrane?

A

attached to the outside and allow the cell to recognize itself

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6
Q

What do Glycolipids do in the cell membrane?

A

phospholipids covalently bonded with carbohydrate chains

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7
Q

What do Glycoproteins do in the cell membrane?

A

proteins covalently bonded with carbohydrate chains

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8
Q

What does cholesterol do in the cell membrane?

A

Reduces membrane fluidity by reducing phospholipid movement

Stops membrane from becoming solid at room temp

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9
Q

Explain how Glycolipids and Glycoproteins work

A

Glyco=suger=carbohydrate

lipids=phospolidids

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10
Q

What does selectively permeable mean?

A

the cell membrane selects what it wants to come in and out of the cell
NOT ALLOWED- large, charged and polar things
ALLOWED-small non-polar things

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11
Q

How do large, charged or polar things get through the cell membrane?

A

through glycoprotein channels

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12
Q

Passive transport VS active transport?

A

Passive- molecules move from high concentration to low concentration to establish equilibrium (no energy required)
Active- molecules move from low concentration to high concentration to establish equilibrium (Requires energy)

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13
Q

3 types of passive transport. What is being transported?

A

Diffusion-passive process of moving molecules through the membrane
Osmosis- The diffusion of water due to the concentration gradient of solutes
Facilitated-molecules unable to pass through the membrane (go through a channel or carrier protein)

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14
Q

How can the rate of diffusion be affected?

A

Concentration- bigger C = faster diffusion
Molecular size- smaller substance = faster diffusion
Temp- faster the temp= molecules move faster
Solubility- soluble molecules= will dissolve through the bilayer faster
Charge- charged molecules do not pass easily

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15
Q

What is the Tonicity of a solution?

A

the solute concentration (affects size and shape of cell)

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16
Q

High solute =?

Low solute =?

A

low water

high water

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17
Q

Explain an Isotonic Solution

A

solution concentration is equal on both sides of membrane (equilibrium)

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18
Q

Explain Hypertonic solution

A

higher solute than solvent (less water outside cell)
water moves out of cell
HYPER PEOPLE GET SKINNY

19
Q

Explain Hypotonic solution

A

Lower solute than solvent (more water inside cell)
water moves into the cell and it explodes (Lysis)
HYPOS ARE FAT

20
Q

Water flows from ______ to ________

A

Water flows from hypotonic solution to hypertonic solutions

21
Q

What is crenation?

A

Red blood cells shrinks and shrivels up

22
Q

What is hemolysis

A

Red blood cells swell and may burst

23
Q

What is Plasmolysis?

A

plant cell membrane shrinks and pulls away from cell wall

24
Q

What is turgor pressure?

A

plant cell membrane swells and organ cells are crushed against cell wall

25
What is facilitated diffusion?
Molecules passing through the cell membrane that normally cannot, so they use a channel or carrier protein. Specific channel/protein for each moleule
26
What is active transport?
Molecules move from low concentration to high concentration against the gradient Large charged and polar molecules IONS SUGARS NUCLEOTIDES
27
3 types of active transport
Sodium potassium pump Endocytosis Exocytosis
28
How does the sodium potassium pump work?
Na attaches to carrier protein with ATP and moves across cell membrane Protein pump changes shape so Na can't re-enter but K can enter K attaches and moves across pump resets requires ATP
29
What is endocytosis
Endo=in Movement of molecules from outside the cell to inside by forming a vesicle requires ATP 2 types
30
2 types of endocytosis and how they work?
Phagocytosis-cell eating. large particles are ingested and vesicles form Pinocytosis- cell drinking. small molecules ingested and vesicle forms
31
What is exocytosis?
Exo=out Reverse of endocytosis cell releases contents of vesicle outside the cell
32
Why is cell size important? What is the ideal size/shape
important for function and survival | Smaller and funny shape ideal
33
What four factors regulate cell size?
Surface area/volume ratio- volume increases faster than surface area Metabolic rate- high metabolic rate Nuclear control- to big=nucleus loses control Support- to big=cell will collapse
34
What are enzymes?
Catalysts- speed up chemical reactions without being consumed end in -ase often are proteins hydrolysis reaction
35
Why do we have enzymes?
Speed up reaction rates in low concentration | forms temporary complex (enzyme substrate complex) so reaction can happen at lower temp
36
What is the enzyme active site?
grooves where substrate attaches to enzyme
37
2 models for enzyme attachment?
lock and key model-individual substrate fits perfectly into active site induced fit- substrate binding induces a shape change so substrate can fit
38
What are coenzymes?
enzyme made up of 2 pieces- protein portion and a co-enzyme | Co-enzymes attach at the allosteric site and cause enzyme to change shape in order for substrate to fit
39
Where does the co-enzyme attach?
Allosteric site
40
metabolism
sum of all biochemical reactions
41
Metabolic pathway
organized sequence of reactions from substrates to products
42
What lowers the activation energy of a reaction
Enzymes
43
Factors that affect reaction rate? (PICT)
Concentration- higher=more successful collisions\ Temp-human enzymes are temperature sensitive (above 40 deg =permanent damage) pH- enzymes have optimal pH Inhibitors- chemicals that interfere with enzyme action
44
Types of inhibitors?
Competitive- compete with substrate for activation site non-competitive- binds with allosteric site temporarily changes shape of active site