Cell Cycle Checkpoint proteins Flashcards by Erin Polley | Brainscape

Q

Active cyclin D-cdk4 complex phosphorylated retinoblastoma protein (pRb) in the nucleus

A

G1 checkpoint

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Q

Activated P53-p21 interaction also prevent G1 to S phase transition

A

G1 checkpoint

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Q

controls mitotic entry via cyclin B-cdk2

A

G2 checkpoint

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Q

Spindle assembly checkpoint (SAC), through P53-cdk2-GADD45 cascade, to ensure chromosome segregation is correct

A

Mitotic checkpoint

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