Cell Cycle and Cell Division (last 10 years questions)

Question 1

1. The fruit fly has 8 chromosomes (2n) in each cell. During interphase of Mitosis if the number of chromosomes at G1 phase is 8, what would be the number of chromosomes
   after S phase? (2021)

a. 16
b. 4
c. 32
d. 8

Answer 1

d. 8

Question 2

2. The centriole undergoes duplication during: (2021)

a. Prophase
b. Metaphase
c. G2 phase
d. S-phase

Answer 2

d. S-phase

Question 3

3. Match List-I with List-II (2021)

List-I List-II
A. S phase (i) Proteins are synthesized

B. G2 phase (ii) Inactive phase

C. Quiescent stage (iii) Interval between mitosis and initiation of DNA replication

D. G1 phase (iv) DNA replication

Choose the correct answer from the options given below.
a. A-iv B-ii C-iii D-i
b. A-iv B-i C-ii D-iii
c. A-ii B-iv C-iii D-i
d. A-iii B-ii C-i D-iv

Answer 3

b. A-iv B-i C-ii D-iii

Question 3

4. Identify the correct statement with regard to G1 phase (Gap1) of interphase. (2020)

a. Reorganization of all cell components takes place.
b. Cell is metabolically active, grows but does not replicate its DNA.
c. Nuclear division takes place.
d. DNA synthesis or replication takes place.

Answer 3

b. Cell is metabolically active, grows but does not replicate its DNA.

Question 4

5. Some dividing cells exit the cell cycle and enter vegetative inactive stage.
   This is called quiescent stage (G0). This process occurs at the end of: (2020)

a. G1 phase
b. S phase
c. G2 phase
d. M phase

Answer 4

a. G1 phase

Question 5

6. Match the following events that occur in their respective phases of cell cycle and select the correct option: (2020-Covid)
7. G1 phase (i) Cell grows and organelle duplication
8. S phase (ii) DNA replication and chromosome duplication
9. G2 phase (iii) Cytoplasmic growth
10. Metaphase in M-phase (iv) Alignment of chromosomes(1) (2) (3) (4)
    a. (iii) (iv) (i) (ii)
    b. (iv) (i) (ii) (iii)
    c. (i) (ii) (iii) (iv)
    d. (ii) (iii) (iv) (i)

Answer 5

c. (i) (ii) (iii) (iv)

Question 6

7. The correct sequence of phases of cell cycle is (2019)

a. M → G1 → G2 → S
b. G1 → G2 → S → M
c. S → G1 → G2 → M
d. G1 → S → G2 → M

Answer 6

d. G1 → S → G2 → M

Question 7

8. Cell in G0 phase (2019)

a. Exit the cell cycle
b. Enter the cell cycle
c. Suspend the cell cycle
d. Terminate the cell cycle

Answer 7

a. Exit the cell cycle

Question 8

9. DNA replication in bacteria occurs: (2017-Delhi)

a. During S-phase
b. Within nucleolus
c. Prior to fission
d. Just before transcription

Answer 8

c. Prior to fission

Question 9

10. When cell has stalled DNA replication fork, which checkpoint should be predominantly activated? [OS] (2016 - II)

a. M
b. Both G2/M and M
c. G1/S
d. G2/M

Answer 9

c. G1/S

Question 10

11. During cell growth, DNA synthesis takes place in: (2016 - II)

a. G2 phase
b. M phase
c. S phase
d. G1 phase

Answer 10

c. S phase

Question 11

12. A somatic cell that has just completed the S phase of its cell cycle, as compared to gamete of the same species, has: (2015 Re)

a. Twice the number of chromosomes and four times the amount of DNA

b. Four times the number of chromosomes and twice the amount of DNA

c. Twice the number of chromosomes and twice the amount of DNA

d. Same number of chromosomes but twice the amount of DNA

Answer 11

a. Twice the number of chromosomes and four times the amount of DNA

Question 12

13. During which phase(s) of cell cycle, amount of DNA in a cell remains at 4C level if the initial amount is denoted as 2C? (2014)

a. G2 and M
b. G0 and G1
c. G1 and S
d. Only G2

Answer 12

d. Only G2

Question 13

14. In ‘S’ phase of the cell cycle: (2014)

a. Amount of DNA is reduced to half in each cell
b. Amount of DNA doubles in each cell
c. Amount of DNA remains same in each cell
d. Chromosome number is increased

Answer 13

b. Amount of DNA doubles in each cell

Question 14

15. Which one of the following never occurs during mitotic cell division? (2022)

a. Coiling and condensation of the chromatids
b. Spindle fibres attach to kinetochores of chromosomes
c. Movement of centrioles towards opposite poles
d. Pairing of homologous chromosomes

Answer 14

d. Pairing of homologous chromosomes

Question 15

16. Select the incorrect statement with reference to mitosis: (2022)

a. Splitting of centromere occurs at anaphase.
b. All the chromosomes lie at the equator at metaphase.
c. Spindle fibres attach to centromere of chromosomes
d. Chromosomes decondense at telophase.

Answer 15

c. Spindle fibres attach to centromere of chromosomes

Question 16

17. In a mitotic cycle, the correct sequence of phases is (2020-Covid)

a. G1, S, G2, M
b. M, G1, G2, S
c. G1, G2, S, M
d. S, G1, G2, M

Answer 16

a. G1, S, G2, M

Question 17

18. Attachment of spindle fibers to kinetochores of chromosomes becomes evident in: (2020-Covid)

a. Telophase
b. Prophase
c. Metaphase
d. Anaphase

Answer 17

c. Metaphase

Question 18

19. Which of the following options gives the correct sequence of events during mitosis? (2017-Delhi)

a. Condensation → Nuclear membrane disassembly → Crossing over → Segregation → Telophase

b. Condensation → Nuclear membrane disassembly → Arrangement at equator → Centromere division → Segregation → Telophase

c. Condensation → Crossing over → Nuclear membrane disassembly → Segregation → Telophase

d. Condensation → Arrangement at equator → Centromere division → Segregation → Telophase

Answer 18

b. Condensation → Nuclear membrane disassembly → Arrangement at equator → Centromere division → Segregation → Telophase

Question 19

20. Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is
    expected to occur? [OS] (2017-Delhi)

a. Chromosomes will not condense
b. Chromosomes will be fragmented
c. Chromosomes will not segregate
d. Recombination of chromosome arms will occur

Answer 19

c. Chromosomes will not segregate

Question 20

21. Which of the following is not a characteristic feature during mitosis in somatic cells? (2016 - I)

a. Spindle fibres
b. Disappearance of nucleolus
c. Chromosome movement
d. Synapsis

Answer 20

d. Synapsis

Question 21

23. A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation
    of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in: (2016 - I)

a. Aneuploidy
b. Polyploidy
c. Somaclonal variation
d. Polyteny

Answer 21

b. Polyploidy

Question 21

22. Spindle fibres attach on to: (2016 - I)

a. Telomere of the chromosome
b. Kinetochore of the chromosome
c. Centromere of the chromosome
d. Kinetosome of the chromosome

Answer 21

b. Kinetochore of the chromosome

Question 22

24. A stage in cell division is shown in the figure. Select the answer which gives correct identification of the stage with its characteristics: (2013)

insert an image

a. Telophase Endoplasmic reticulum and nucleolus not reformed yet.

b. Telophase Nuclear envelope reforms, Golgi complex reforms.

c. Late Anaphase Chromosomes move away from equatorial plate, Golgi complex not present.

d. Cytokinesis Cell plate formed, mitochondria distributed between two daughter cells.

Answer 22

b. Telophase Nuclear envelope reforms, Golgi complex reforms.

Question 23

25. The appearance of recombination nodules on homologous chromosomes during meiosis characterizes? (2022) a. Terminalization b. Synaptonemal complex c. Bivalent d. Sites at which crossing over occurs

Answer 23

d. Sites at which crossing over occurs

Question 24

26. Regarding Meiosis, which of the statements is incorrect? (2022) a. Four haploid cells are formed at the end of Meiosis-II b. There are two stages in Meiosis, Meiosis-I and II c. DNA replication occurs in S phase of Meiosis-II d. Pairing of homologous chromosomes and recombination occurs in Meiosis-I

Answer 24

c. DNA replication occurs in S phase of Meiosis-II

Question 25

27. Which stage of meiotic prophase shows terminalization of chiasmata as its distinctive feature? (2021) a. Zygotene b. Diakinesis c. Pachytene d. Leptotene

Answer 25

b. Diakinesis

Question 26

28. Which of the following stages of meiosis involves division of centromere? (2021) a. Metaphase II b. Anaphase II c. Telophase II d. Metaphase I

Answer 26

b. Anaphase II

Question 27

29. Match the following with respect to meiosis: (2020) Column-I Column-II 1. Zygotene (i) Terminalization 2. Pachytene (ii) Chiasmata 3. Diplotene (iii) Crossing over 4. Diakinesis (iv) Synapsis Select the correct option from the following: (1) (2) (3) (4) a. (iv) (iii) (ii) (i) b. (i) (ii) (iv) (iii) c. (ii) (iv) (iii) (i) d. (iii) (iv) (i) (ii)

Answer 27

a. (iv) (iii) (ii) (i)

Question 28

30. Dissolution of the synaptonemal complex occurs during: (2020) a. Zygotene b. Diplotene b. Leptotene d. Pachytene

Answer 28

b. Diplotene

Question 29

31. During Meiosis I, in which stage synapsis takes place? (2020-Covid) a. Zygotene b. Diplotene c. Leptotene d. Pachytene

Answer 29

a. Zygotene

Question 30

32. The stage during which separation of the paired homologous chromosomes begins is (2018) a. Pachytene b. Diplotene c. Diakinesis d. Zygotene

Answer 30

b. Diplotene

Question 31

33. Match the stages of meiosis in Column-I to their characteristic features in Column-II and select the correct option using the codes given below: (2016 - II) Column-I Column-II A. Pachytene i. Pairing of homologous chromosomes B. Metaphase-I ii. Terminalization of chiasmata C. Diakinesis iii. Crossing over takes place D. Zygotene iv. Chromosomes align at equatorial plate Codes: a. A-ii B-iv C-iii D-i b. A-iv B-iii C-ii D-i c. A-iii B-iv C-ii D-i d. A-i B-iv C-ii D-iii

Answer 31

c. A-iii B-iv C-ii D-i

Question 32

34. In meiosis, crossing over is initiated at: (2016 - I) a. Pachytene b. Leptotene c. Zygotene d. Diplotene

Answer 32

a. Pachytene

Question 33

35. Select the correct option: (2015) Column-I Column-II A. Synapsis aligns the homologous chromosomes i. Anaphase-II B. Synthesis of RNA and protein ii. Zygotene C. Action of enzyme recombinase iii. G2-phase D. Centromeres do not separate but iv. Anaphase-I chromatids move towards opposite poles v. Pachytene a. A-i B-ii C-iii D-iv b. A-ii B-iii C-iv D-v c. A-ii B-i C-iii D-iv d. A-ii B-iii C-v D-iv

Answer 33

d. A-ii B-iii C-v D-iv

Question 34

36. Arrange the following events of meiosis in correct sequence: (2015 Re) A. Crossing over B. Synapsis C. Terminalization of chiasmata D. Disappearance of nucleolus a. (B), (A), (C), (D) b. (A), (B), (C), (D) c. (B), (C), (D), (A) d. (B), (A), (D), (C)

Answer 34

a. (B), (A), (C), (D)

Question 35

37. The enzyme recombinase is required at which stage of meiosis? (2014) a. Diakinesis b. Pachytene c. Zygotene d. Diplotene

Answer 35

b. Pachytene

Question 36

38. The complex formed by a pair of synapsed homologous chromosomes is called: (2013) a. Axoneme b. Equatorial plate c. Kinetochores d. Bivalent

Answer 36

d. Bivalent