Cell Cycle and Cell Division (last 10 years questions) Flashcards

1
Q
  1. The fruit fly has 8 chromosomes (2n) in each cell. During interphase of Mitosis if the number of chromosomes at G1 phase is 8, what would be the number of chromosomes
    after S phase? (2021)

a. 16
b. 4
c. 32
d. 8

A

d. 8

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2
Q
  1. The centriole undergoes duplication during: (2021)

a. Prophase
b. Metaphase
c. G2 phase
d. S-phase

A

d. S-phase

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3
Q
  1. Match List-I with List-II (2021)

List-I List-II
A. S phase (i) Proteins are synthesized

B. G2 phase (ii) Inactive phase

C. Quiescent stage (iii) Interval between mitosis and initiation of DNA replication

D. G1 phase (iv) DNA replication

Choose the correct answer from the options given below.
a. A-iv B-ii C-iii D-i
b. A-iv B-i C-ii D-iii
c. A-ii B-iv C-iii D-i
d. A-iii B-ii C-i D-iv

A

b. A-iv B-i C-ii D-iii

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3
Q
  1. Identify the correct statement with regard to G1 phase (Gap1) of interphase. (2020)

a. Reorganization of all cell components takes place.
b. Cell is metabolically active, grows but does not replicate its DNA.
c. Nuclear division takes place.
d. DNA synthesis or replication takes place.

A

b. Cell is metabolically active, grows but does not replicate its DNA.

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4
Q
  1. Some dividing cells exit the cell cycle and enter vegetative inactive stage.
    This is called quiescent stage (G0). This process occurs at the end of: (2020)

a. G1 phase
b. S phase
c. G2 phase
d. M phase

A

a. G1 phase

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5
Q
  1. Match the following events that occur in their respective phases of cell cycle and select the correct option: (2020-Covid)
  2. G1 phase (i) Cell grows and organelle duplication
  3. S phase (ii) DNA replication and chromosome duplication
  4. G2 phase (iii) Cytoplasmic growth
  5. Metaphase in M-phase (iv) Alignment of chromosomes(1) (2) (3) (4)
    a. (iii) (iv) (i) (ii)
    b. (iv) (i) (ii) (iii)
    c. (i) (ii) (iii) (iv)
    d. (ii) (iii) (iv) (i)
A

c. (i) (ii) (iii) (iv)

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6
Q
  1. The correct sequence of phases of cell cycle is (2019)

a. M → G1 → G2 → S
b. G1 → G2 → S → M
c. S → G1 → G2 → M
d. G1 → S → G2 → M

A

d. G1 → S → G2 → M

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7
Q
  1. Cell in G0 phase (2019)

a. Exit the cell cycle
b. Enter the cell cycle
c. Suspend the cell cycle
d. Terminate the cell cycle

A

a. Exit the cell cycle

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8
Q
  1. DNA replication in bacteria occurs: (2017-Delhi)

a. During S-phase
b. Within nucleolus
c. Prior to fission
d. Just before transcription

A

c. Prior to fission

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9
Q
  1. When cell has stalled DNA replication fork, which checkpoint should be predominantly activated? [OS] (2016 - II)

a. M
b. Both G2/M and M
c. G1/S
d. G2/M

A

c. G1/S

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10
Q
  1. During cell growth, DNA synthesis takes place in: (2016 - II)

a. G2 phase
b. M phase
c. S phase
d. G1 phase

A

c. S phase

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11
Q
  1. A somatic cell that has just completed the S phase of its cell cycle, as compared to gamete of the same species, has: (2015 Re)

a. Twice the number of chromosomes and four times the amount of DNA

b. Four times the number of chromosomes and twice the amount of DNA

c. Twice the number of chromosomes and twice the amount of DNA

d. Same number of chromosomes but twice the amount of DNA

A

a. Twice the number of chromosomes and four times the amount of DNA

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12
Q
  1. During which phase(s) of cell cycle, amount of DNA in a cell remains at 4C level if the initial amount is denoted as 2C? (2014)

a. G2 and M
b. G0 and G1
c. G1 and S
d. Only G2

A

d. Only G2

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13
Q
  1. In ‘S’ phase of the cell cycle: (2014)

a. Amount of DNA is reduced to half in each cell
b. Amount of DNA doubles in each cell
c. Amount of DNA remains same in each cell
d. Chromosome number is increased

A

b. Amount of DNA doubles in each cell

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14
Q
  1. Which one of the following never occurs during mitotic cell division? (2022)

a. Coiling and condensation of the chromatids
b. Spindle fibres attach to kinetochores of chromosomes
c. Movement of centrioles towards opposite poles
d. Pairing of homologous chromosomes

A

d. Pairing of homologous chromosomes

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15
Q
  1. Select the incorrect statement with reference to mitosis: (2022)

a. Splitting of centromere occurs at anaphase.
b. All the chromosomes lie at the equator at metaphase.
c. Spindle fibres attach to centromere of chromosomes
d. Chromosomes decondense at telophase.

A

c. Spindle fibres attach to centromere of chromosomes

16
Q
  1. In a mitotic cycle, the correct sequence of phases is (2020-Covid)

a. G1, S, G2, M
b. M, G1, G2, S
c. G1, G2, S, M
d. S, G1, G2, M

A

a. G1, S, G2, M

17
Q
  1. Attachment of spindle fibers to kinetochores of chromosomes becomes evident in: (2020-Covid)

a. Telophase
b. Prophase
c. Metaphase
d. Anaphase

A

c. Metaphase

18
Q
  1. Which of the following options gives the correct sequence of events during mitosis? (2017-Delhi)

a. Condensation → Nuclear membrane disassembly → Crossing over → Segregation → Telophase

b. Condensation → Nuclear membrane disassembly → Arrangement at equator → Centromere division → Segregation → Telophase

c. Condensation → Crossing over → Nuclear membrane disassembly → Segregation → Telophase

d. Condensation → Arrangement at equator → Centromere division → Segregation → Telophase

A

b. Condensation → Nuclear membrane disassembly → Arrangement at equator → Centromere division → Segregation → Telophase

19
Q
  1. Anaphase promoting complex (APC) is a protein degradation machinery necessary for proper mitosis of animal cells. If APC is defective in a human cell, which of the following is
    expected to occur? [OS] (2017-Delhi)

a. Chromosomes will not condense
b. Chromosomes will be fragmented
c. Chromosomes will not segregate
d. Recombination of chromosome arms will occur

A

c. Chromosomes will not segregate

20
Q
  1. Which of the following is not a characteristic feature during mitosis in somatic cells? (2016 - I)

a. Spindle fibres
b. Disappearance of nucleolus
c. Chromosome movement
d. Synapsis

A

d. Synapsis

21
Q
  1. A cell at telophase stage is observed by a student in a plant brought from the field. He tells his teacher that this cell is not like other cells at telophase stage. There is no formation
    of cell plate and thus the cell is containing more number of chromosomes as compared to other dividing cells. This would result in: (2016 - I)

a. Aneuploidy
b. Polyploidy
c. Somaclonal variation
d. Polyteny

A

b. Polyploidy

21
Q
  1. Spindle fibres attach on to: (2016 - I)

a. Telomere of the chromosome
b. Kinetochore of the chromosome
c. Centromere of the chromosome
d. Kinetosome of the chromosome

A

b. Kinetochore of the chromosome

22
Q
  1. A stage in cell division is shown in the figure. Select the answer which gives correct identification of the stage with its characteristics: (2013)

insert an image

a. Telophase Endoplasmic reticulum and nucleolus not reformed yet.

b. Telophase Nuclear envelope reforms, Golgi complex reforms.

c. Late Anaphase Chromosomes move away from equatorial plate, Golgi complex not present.

d. Cytokinesis Cell plate formed, mitochondria distributed between two daughter cells.

A

b. Telophase Nuclear envelope reforms, Golgi complex reforms.

23
Q
  1. The appearance of recombination nodules on homologous chromosomes during meiosis characterizes? (2022)

a. Terminalization
b. Synaptonemal complex
c. Bivalent
d. Sites at which crossing over occurs

A

d. Sites at which crossing over occurs

24
Q
  1. Regarding Meiosis, which of the statements is incorrect? (2022)

a. Four haploid cells are formed at the end of Meiosis-II

b. There are two stages in Meiosis, Meiosis-I and II

c. DNA replication occurs in S phase of Meiosis-II

d. Pairing of homologous chromosomes and recombination occurs in Meiosis-I

A

c. DNA replication occurs in S phase of Meiosis-II

25
Q
  1. Which stage of meiotic prophase shows terminalization of chiasmata as its distinctive feature? (2021)

a. Zygotene
b. Diakinesis
c. Pachytene
d. Leptotene

A

b. Diakinesis

26
Q
  1. Which of the following stages of meiosis involves division of centromere? (2021)

a. Metaphase II
b. Anaphase II
c. Telophase II
d. Metaphase I

A

b. Anaphase II

27
Q
  1. Match the following with respect to meiosis: (2020)

Column-I Column-II

  1. Zygotene (i) Terminalization
  2. Pachytene (ii) Chiasmata
  3. Diplotene (iii) Crossing over
  4. Diakinesis (iv) Synapsis

Select the correct option from the following:

 (1) (2) (3) (4) a. (iv) (iii) (ii) (i) b. (i) (ii) (iv) (iii) c. (ii) (iv) (iii) (i) d. (iii) (iv) (i) (ii)
A

a. (iv) (iii) (ii) (i)

28
Q
  1. Dissolution of the synaptonemal complex occurs during: (2020)

a. Zygotene
b. Diplotene
b. Leptotene
d. Pachytene

A

b. Diplotene

29
Q
  1. During Meiosis I, in which stage synapsis takes place? (2020-Covid)

a. Zygotene
b. Diplotene
c. Leptotene
d. Pachytene

A

a. Zygotene

30
Q
  1. The stage during which separation of the paired homologous chromosomes begins is (2018)

a. Pachytene
b. Diplotene
c. Diakinesis
d. Zygotene

A

b. Diplotene

31
Q
  1. Match the stages of meiosis in Column-I to their characteristic features in Column-II and select the correct option using the codes given below: (2016 - II)

Column-I Column-II

A. Pachytene i. Pairing of homologous chromosomes

B. Metaphase-I ii. Terminalization of chiasmata

C. Diakinesis iii. Crossing over takes place

D. Zygotene iv. Chromosomes align at equatorial plate

Codes:
a. A-ii B-iv C-iii D-i
b. A-iv B-iii C-ii D-i
c. A-iii B-iv C-ii D-i
d. A-i B-iv C-ii D-iii

A

c. A-iii B-iv C-ii D-i

32
Q
  1. In meiosis, crossing over is initiated at: (2016 - I)

a. Pachytene
b. Leptotene
c. Zygotene
d. Diplotene

A

a. Pachytene

33
Q
  1. Select the correct option: (2015)

Column-I Column-II

A. Synapsis aligns the homologous chromosomes i. Anaphase-II

B. Synthesis of RNA and protein ii. Zygotene

C. Action of enzyme recombinase iii. G2-phase

D. Centromeres do not separate but iv. Anaphase-I
chromatids move towards opposite
poles

                                                                                                  v. Pachytene

a. A-i B-ii C-iii D-iv
b. A-ii B-iii C-iv D-v
c. A-ii B-i C-iii D-iv
d. A-ii B-iii C-v D-iv

A

d. A-ii B-iii C-v D-iv

34
Q
  1. Arrange the following events of meiosis in correct sequence:
    (2015 Re)

A. Crossing over
B. Synapsis
C. Terminalization of chiasmata
D. Disappearance of nucleolus

a. (B), (A), (C), (D)
b. (A), (B), (C), (D)
c. (B), (C), (D), (A)
d. (B), (A), (D), (C)

A

a. (B), (A), (C), (D)

35
Q
  1. The enzyme recombinase is required at which stage of meiosis? (2014)

a. Diakinesis
b. Pachytene
c. Zygotene
d. Diplotene

A

b. Pachytene

36
Q
  1. The complex formed by a pair of synapsed homologous chromosomes is called: (2013)

a. Axoneme
b. Equatorial plate
c. Kinetochores
d. Bivalent

A

d. Bivalent