Cell Biology Flashcards
Cytology vs cell physiology
Study of cellular structure vs study of cellular function
Resolution
The ability to distinguish between two points
Most common way to look at cells
Light microscope.
- Compound
- Dissecting
Can view the cell mitochondria and 1 micro meter
Scanning tunneling microscope
Very new technology can view 0.001 micrometers. The size of a protein molecule.
Confocal microscope
Higher resolution. Optically slices tissues so there is no out of focus tissue.
Electron microscope types
Transmission, scanning, x ray detector
Nuclear division
Mitosis
Cytoplasmic division
Cytokinesis
Mitosis
One parent somatic cell gives rise to two identical daughter cells
Meiosis
Reproductive cell division that produces eggs and sperm. Occurs only in the testes and ovary.
Largest organelle in a cell
Nucleus (surrounded by 2 membranes)
DNA polymerase creates DNA in which direction
DNA polymerase can only add onto the 3’ OH end of a DNA strand.
Post-transcriptional modification to mRNA
- 5’ cap
- 3’ poly A tail
- Splice out introns, leaving only exons to exit the nucleus.
Polyribosome
10-20 ribosomes together
Where can ribosomes be found
Free in the cytoplasm, on the RER, and inside the mitochondria to synthesize mitochondrial DNA
Polar amino acids
Have OH groups and hydrogen bonds
Primary protein structure
Single strand of amino acids
Secondary protein structure
Alpha helix or beta pleated sheets