celiac disease Flashcards
1
Q
autoimmune disorder of small intestine with intolerance to gliadin (gluten, wheat)
wheat protein cross-reacts with small bowel tissue → inflammation → malabsorption
A
celiac disease
2
Q
anti-gliadin Abs
anti-tissue transglutaminase Abs
anti-endomysial Abs
A
celiac disease
3
Q
blunting of villi + macrovilli
foul-smelling, pale stools
stunted growth
failure to thrive
A
celiac disease
4
Q
treatment
A
gluten-free diet
5
Q
associated with HLA-DQ2 and HLA-DQ8
A
celiac disease
6
Q
complications of celiac disease
A
↑ risk
T cell lymphoma
GI cancer
breast cancer
