CD-Q

Question 1

Expressed by monocytes, macrophages and neutrophils (“cell surface marker of macrophages”)

Interacts with the LPS-LPS binding protein complex to activate effector cells

Answer 1

CD14

Question 2

Protein localized to inter endothelial junctions.

Antibodies to this identifies endothelial cells histochemically

Answer 2

CD31

Question 3

Attaches to host cells via glycophosphatidylinositol anchor.

Prevent C9 from polymerizing and activating MAC.

Not seen in PNH

Answer 3

CD59

Question 4

Aka decay accelerating factor.

Prevent assembly of C3bBb complex

Answer 4

CD55

Question 5

Pan B-cell markers

Answer 5

CD19

CD20

Question 7

Lineage specific marker of T cells

Answer 7

CD3

Question 8

Expressed by RS cells, seen in Hodgkin lymphoma

Answer 8

CD15

CD30

Question 9

Expressed in hairy cell leukemia

Answer 9

CD11c

CD103

Question 10

Expressed in CLL and mantle cell lymphoma

Answer 10

CD5

Question 11

Expressed by T cell leukemia caused by HTLV1

Answer 11

CD25

Question 12

Costimulatory signal necessary for T-cell activation

Answer 12

CD28

Question 13

Death receptor in many cells aka Fas

Answer 13

CD95

Question 14

Selectins have this CD number

Answer 14

CD62

Question 15

NK cells express this Fc receptor which allows it to phagocytize opsonized cells

Answer 15

CD16