Causes Of Cancer Flashcards
Cancer often only appears after a sequence of…
Separate events.
Many different types of cancer, caused by different factors
Genetic factors:
Some people have proto-oncogenes which are more likely to mutate than others
Why some types or cancer are more common in some families than others - e.g. breast cancer, BRCA1 and BRCA2 that increase the chances a person will get breast cancer
Age: older you are more likely you are to suffer from cancer, partly because they have had…
More years of exposure to environmental factors (ionising radiation and carcinogens)
Also because they are older they have had the chance to accumulate damage to their DNA
Ionising radiation: this includes X rays, alpha and beta radiation
Contains a great deal or energy so penetrates bonds in DNA molecules
Ultraviolet radiation: has less ionising radiation, but does ave enough energy to penetrate skin cells (sunburn)
It breaks…
Bonds in the DNA of skin cells and can cause skin cancer
Chemicals: many chemicals can cause cancer, these are called…
Carcinogens
Cigarette smoke contains several different carcinogens
Asbestos fibres, some pesticides and diesel exhaust can also cause cancer
Viruses:
Best-known one is human papilloma virus, some kinds can cause cervical cancer.
Types of the HPV carry the code for a protein that interfere with a tumour-suppressor gene
HPV is passed on through sexual inter course