5.2 B Cells Flashcards
B cells develop in the…
Bone marrow
As B cells develop they produce…
Small quantities of antibodies, however at this stage the antibodies are attached to the plasma membrane of the B cell
Each kind of B cell has a…
Slightly different shape of antibody on its surface
The macrophages move to the lymph nodes where they…
- Display it’s antigens to all the different kinds of B cells
- When a B cell with the right shape of antibody passes the macrophage the antigen and antibody will fit together
- Stimulating that particular B cell to divide repeatedly, making many identical copies of itself (clonal selection)
Clonal selection is…
The process by which a B cell with the right receptor to a specific antigen is stimulated to divide
Many of the cells or clones formed by the dividing B cell become…
Plasma cells
Plasma cells rapidly produce…
-Large amounts of their specific antibody
Antibodies from the plasma cell are…
Released into the blood, where they bind to the antigens on the bacteria - causing the bacteria to be destroyed
Some of the cells produced by the dividing B cell become…
Memory cells
Memory cells…
Remain in the blood for a long time and carry an IMMUNOLOGICAL
MEMORY of the original antigen
Immunological memory means…
If the same antigen enters the body again, the same memory B cells will be able to produce specific antibodies very quickly - active immunity
