catabolism of pyruvate Flashcards
1
Q
what is NAD derived from
A
niacin, a vitamin
2
Q
how does pyruvate enter the mitochondrial matrix
A
H/pyruvate symport by facilitated diffusion
3
Q
what are the product of the TCA cycle
A
3 NADH
1 GTP
1 FADH2
2CO2
4
Q
which enzyme is located on the inner mitochondrial membrane
A
succinate dehydrogenase
5
Q
what is the yield from one molecule of glucose
A
4 ATP 10 NADH 10 H 2 FADH 4 CO2
6
Q
what does PDC to
A
convert pyruvate to acetyl - CoA
irreversible
7
Q
what does PDC deficiency cause
A
poor muscle tone and lack of coordination
retardation and seizures
resp problems
