catabolism of glucose Flashcards
name 2 polysaccharides
cellulose and glycogen
name 3 fates of glucose
lactate
pyruvate
ribose 5 phosphate
what GLUT are found in the brain
1 and 3
how many molecules of pyruvate does one molecules of glucose make
2
glucose 6C and pyruvate 3C
what does hexokinase control
substrate entry
what does phosphofructokinase control
rate of flow
what does pyruvate kinase control
product exit
what reactoin does phosphofructokinase control
fructose 6-phosphate + ATP to fructose 1,6-bisphosphate + ADP + H+
what is the effect of AMP on phosphofructokinase
inc glycolysis if energy needed
wha are the inhibitors of phosphofructokinase
citrate, ATP and H
what does H do to phosphofructokinase
prevent excess lactic acid production
what is the ATP/AMP ratio called
the energy change
what happens if mitochondrial metabolism is inhibited by lack of oxygen
NADH is used to
ferment pyruvate to
lactic acid (lactate)
NADH is regenerated then
what is the warburg effect
cancer cells produce energy by high rate of glucose metabolism to lactate
Cancer cells have low KM Hexokinase
what are the advantages of the warburg effect
rapid energy production
support other pathways and rapid cell growth
