Case Study: Quantitative and Qualitative Platelet Disorder Flashcards

1
Q
  • Prolonged bleeding time
  • Larged size platelet
  • decreased platelet count
  • Decreased or absent response to ristocetin-induced aggregation
  • Normal plasma vWF and factor VIII
  • Normal response to agonist
A

Bernard-Soulier Syndrome

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2
Q
Prolonged bleeding time
Impaired clot retraction
Normal PT, APTT,and thrombin time
Decreased Platelet antigen PAI1
reduced ang response sa agonist such as ADP, collagen, epinephrine and arachidonic acid
A

Glanzmann Thrombasthenia

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