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F16: Anatomy Test 3 > Cartilage > Flashcards

Cartilage Flashcards

1
Q

Two methods for growth in cartilage?

A

Appositional Growth & Interstitial Growth

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2
Q

Interstitial Growth

A

Growth by internal expansion; proliferation of chondrocytes and formation of isogenous groups

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3
Q

Appositional Growth

A

Growth by addition to existing surface; generation of new chondroblasts

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4
Q

Major two cells in cartilage?

A

Chondroblasts & chondrocytes

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5
Q

Extracellular Matrix makeup?

A

Makes up 95% of cartilage.

Rich in glycosaminoglycans & proteoglycans.

Allows for withstanding mechanical forces; very resilient

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6
Q

Three types of cartilage?

A

Hyaline Cartilage
Elastic Cartilage
Fibrocartilage

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7
Q

Hyaline Cartilage: ECM composition and perichondrium?

A

75% water, proteoglycans, hyaluronic acid, type II collagen

Perichondrium: present (with few exceptions)

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8
Q

Hyaline Cartilage: location?

A

Articulate surfaces, nose, larynx, tracheal rings, epiphyseal plates, fetal bone models

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9
Q

Hyaline Cartilage: appearence?

A

Dissection: Bluish white and translucent

Histo: matrix is generally basophilic; in routine staining, collagen fibers are indiscernible

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10
Q

Which type of cell can add extracellular matrix?

A

Both chondrocytes (interstitial growth) and chondroblasts (appositional growth).

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11
Q

Isogenous groups Indicate what in a histo slide?

A

Indicates interstitial growth.

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12
Q

Territorial matrix vs interterritorial matrix?

A

Territorial: heavy purple close to cells; more GAGs less collagen

Interterritorial: light purple/pink between cells; more collagen less GAGs

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13
Q

Elastic Cartilage: ECM composition and perichondrium?

A

Essentially the same as hyaline cartilage with the addition of elastic fibers

Perichondrium present

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14
Q

Elastic Cartilage: location?

A

Auricle, auditory canal, auditory tube, epiglottis

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15
Q

Elastic Cartilage: appearance?

A

Dissection: yellowish color

Histo: with special staining, elastic fibers are prominent between chondrocytes and lacunae

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16
Q

Special characteristics of Elastic cartilage in epiglottis?

A

With age, cartilage shrinks and is replaced with adipose cells.

17
Q

Elastic vs hyaline cartilage?

A

More chondrocytes in elastic cartilage than hyaline.

However, less isogenous groups in elastic cartilage.

18
Q

Fibrocartilage: ECM and perichondrium?

A

Type I collagen, less proteoglycans than other cartilages

Perichondrium: absent

19
Q

Fibrocartilage: location and why?

A

Places with lots of pulling forces.

Good intermediate between dense connective tissue and cartilage.

Intervertebral discs, pubic symphysis, major tendon-bone anchorages

20
Q

Fibrocartilage: appearance?

A

Histo: chondrocytes arranged in long rows separated by coarse collagen fibers; matrix is more acidophilic

F16: Anatomy Test 3 (11 decks)

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