cardiovascular system-blood: hemoglobin 08/22 Flashcards
Hb
hemoglobin
what does hemoglobin transport
oxygen
what is the equation for oxyhemoglobin
O2+Hb—> oxyhemoglobin
what percentage of oxygen from lungs to tissue is attached to what?
90-98% of the oxygen is attached to hemoglobin
what percentage of oxygen from lungs to tissue is dissolved in plasma?
2% of the oxygen from lungs to tissue is dissolved in plasma
rupture of red blood cells renders _____ nonfunctional
hemoglobin
causes of hemolysis
hemolytic anemia
transfusions
hemolytic disease of the newborn
malaria
CO2 + Hb from ____ —-> ____
CO2 + Hb from cells —-> lungs
erthryopoiesis is the production of
erythrocytes
leukopoiesis is the production of
leukocytes
thrombopoiesis is the production of
thrombocytes
what is the structure of Hemoglobin
2 alpha chains
2 beta chains
on each chain there is a ring of Hem
In each Hem there is an Iron ion
80% of ___ is transported as _______ ____ produced as a result of the combination of ____ and ____
80% of CO2 is transported as bicarbonate ions produced as a result of the combination of H2O and CO2
what are the 2 types of hemoglobin?
fetal and embryonic hemoglobin
adult hemoglobin
fetal and embryonic hemoglobin has a greater ____ for ___ than ____
fetal and embryonic hemoglobin has a greater attraction (affinity) for oxygen than adult
fetal production stops after
birth
adult hemoglobin bound to
substances like:
oxygen, carbon monoxide, carbon dioxide
adult hemoglobin contains what kind of hemoglobins
oxyhemoglobin
deoxyhemoglobin
carbaminohemoglobin
carboxyhemoglobin
oxyhemoglobin
transporting oxygen
deoxyhemoglobin
without oxygen
carbaminohemoglobin
transporting carbon dioxide
carboxyhemoglobin
bound to carbon monoxide
very strong and stable
unable to transport oxygen
genetic diseases of blood
sickle cell anemia
malaria
sickle cell anemia
RBC are not circular and cannot transport oxygen
malaria
RBCs become anemic
people who have genetic diseases are provided with
fetal hemoglobin
proerythroblast
newly formed
have a nucleus
reticulocyte
matured
do not have a nucleus
normoblast
ejection of nucleus
anemia
decrease in oxygen capacity in the blood
decrease in the erythrocytic level
decrease in vitamin B12, D
Hemoglobin deficient
erythropoietin is produced by
kidneys
what is a must for erythrocytes
vitamins: B12, C, follic acid
elements: Iron, Cu, Mn