Cardiovascular System Flashcards
1
Q
Circulatory System
A
- one of two vascular systems in the body
- Circulates blood, uses heart as a pump
2
Q
Lymphoid System
A
- one of two vascular systems in the body
- Unidirectional
- No pump
- Lymphatic fluid will be drained in the lymph nodes and will make its way into the circulatory system
3
Q
Capillaries
A
- Lined by single layer of endothelial cells
- Connected by cell junctions
- Has a basal lamina outside around endothelial cell
- Contains pericytes around basal lamina which provide nutrients and maintain viability of endothelial cells
4
Q
Continuous Capillary
A
- most common
- found in muscle, skin, lung and brain
5
Q
Fenstrated Capillary
A
- Located in intestines, endocrine system, kidneys
- In the kidneys there is a thick basement membrane and no diaphragm
- have fenstrations spanned by diaphragms
6
Q
Sinusoidal (discontinuous) capillaries
A
- Located in liver, spleen, bone marrow and endocrine system
- Contain large holes (gaps) where an entire cell can squeeze through
7
Q
Capillary Exchange Mechanisms
A
- Open pores/gaps
- Diffusion
- Filtration
- Vesicular transport (transcytosis)
- Transendothelial channels- Vesciles join together to form a channel - allows rapid movement of cells
8
Q
Vesicular Transport
A
- Mechanism of capillary exchange
- System of pinocytotic pits and vesicles which move large molecules across the endothelium
9
Q
Secretory and Metabolic Functions of Endothelial Cells
A
- Adhesion molecules (diapedesis)
- Produce vasoactive compounds ( NO for vasodilation, endothelin for vasoconstriction
- Anti thrombogenic factors (anti clotting)
- Metabolic conversions (angiotensin I to II, vasoconstriction)
10
Q
Tunica Intima
A
- Endothelium
- Connective Tissue
- Internal Elastic Lamina (IEL)
11
Q
Tunica Media
A
- Smooth Muscle
- Elastic Fibers
- External Elastic Lamina (EEL)
- Thicker in arteries, thinner in veins
12
Q
Tunica Adventitia
A
- Connective Tissue
- vasa vorum
- nerves
- Thinner in arteries, thicker in veins
13
Q
Elastic Arteries (aorta)
A
- Large Lumen
- Thick tunica interna
- 40+ layers of smooth muscle in tunica media
- Thin Tunica adventitia
- A lot of elastic fibers throughout tunica media
- needs to have elasticity of aorta for it to expand and contract with the pumping of the heart
14
Q
Muscular (Distributing) Arteries
A
- Thin tunica intima
- up to 40 layers of smooth muscle in tunica media
- thin tunica adventitia
- Internal and external elastic laminas
- elastic lamina’s looked scalloped due to no longer being under pressure
15
Q
Arteriole
A
- Smaller lumen
- Thin tunica intima
- 2-5 layers of smooth muscle in the tunica media
- Thin tunica adventitia
- may or may not have internal elastic lamina