Cardiopathology III Flashcards
list the primary heart tumors
rhabdomyoma
mesothelioma
chemodectoma
hemangiosarcoma
describe rhabdomyoma
cardiac muscle cells - very rare
pale/grey nodules in myocardium of heart
describe mesothelioma
mesothelial cells lining serosa surface - can be nodular OR carpet-like
rare-uncommon
causes pericardial effusion
ID pathology
rhabdomyoma
ID pathology
mesothelioma
ID pathology
mesothelioma
describe chemodectoma
aka heart base aka aortic body tumor
uncommon in dogs - brachycephalics common
arise from extra-cardiac chemoreceptor tissue at heart base between aorta and pulmonary artery
what’s the main HF mechanism regarding chemodectoma?
obstructed flow through heart - specifically pulmonary artery
ID pathology
chemodectoma
describe gross and histological appearance of chemodectoma
ID pathology
chemodectoma
ID pathology
chemodectoma
what are the complications/outcomes of chemodectoma?
locally invasive
compresses surrounding structures
*may be benign or malignant
describe hemangiosarcoma
neoplasm of endothelial cells of blood vessels
VERY common
*primary tumors are usually in R auricle area OR develop in spleen/liver
most common in goldens and germans
ID pathology
hemangiosarcoma
describe gross and histological appearance of hemangiosarcoma
what are the common outcomes of hemangiosarcoma?
***metastatizes
rupture > hemorrhage into pericardium > hemopericardium +/- tamponade
ID pathology
hemangiosarcoma
ID pathology
hemangiosarcoma
describe malignant lymphoma
most common secondary cardiac neoplasm
common in cows - HULA locations, dog, cat
ID pathology
malignant lymphoma
describe gross and histological appearance of malignant lymphoma
Liz Brain
ID pathology
arterial hypertrophy
list causes of hypertrophy in cats, cattle, and general species
cat - parasite
cattle - brisket disease
L to R shunts
chronic P (hypertension) or volume overload
describe brisket disease
cows at high altitude
hypoxic environment > pulmonary hypertension
young»_space; old affected
brisket disease pathogenesis
high altitude pulmonary arteries vasoconstriction > hypertrophy of arterial walls > dilation and hypertrophy of R ventricle (cor pulmonale) > R side CHF > ventral edema
ID pathology
brisket disease - hypertrophy
Liz Brain terms
describe feline infectious peritonitis (FIP)
phlebitis (vein inflame)
pyogranulomatous inflammation (macrophage)
young cats
*effusive and noneffusive forms (wet/dry)
wet FIP is type ___ hypersensitivity and dry is ___ hypersensitivity
wet - type III
dry - type IV
which form of FIP has most increased vascular permeability?
wet
causes edema - dec oncotic P
ID pathology
FIP
ID pathology
FIP
describe heartworm disease
Dirofilaria immitis
matures in pulmonary arteries
andarteritis - eosinophil infiltration of intima
pulmonary infarct due to thromboemboli
caval syndrome
what’s caval syndrome in heartworm disease?
liver failure - R heart backup
hemolytic anemia - parasites eat RBC
cardiogenic shock
ID pathology
heartworm disease - arteritis
describe gross and radiograph appearance of heartworm disease
SLIDE 18