Cardiology (Week 5) Flashcards

1
Q

Name two main features that characterise heart failure?

A

Systemic vasoconstriction and neurohumoral activation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

List three causes of heart failure

A
  1. MI
  2. Hypertension
  3. Idiopathic
  4. Alcohol
  5. Chemotherapy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Name a common sign of heart failure

A

Displaced apex beat
3rd heart sound
Elevated JVP

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What class of drugs are used for symptomatic relief in heart failure but do not improve outcomes

A

Diuretics

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What does a neprilysin inhibitor do in terms of heart failure treatment?

A

Inhibits neprilysin, an enzyme which breaks down natriuretic peptides whose function is to cause vasodilation and diuresis (maintain this as is beneficial to HF)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Why should ACE inhibitors and angiotensin receptor blockers never be given together?

A

Because they both prevent the breakdown of bradykinin which causes cough and angioedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What do low natriuretic peptides mean in terms of heart failure diagnosis?

A

That the patient does not have heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are Kerley B lines?

A

Fluid moving into the interstitial space and causing pressure build up in vessel s, appearing as small, white straight lines on the edge of chest X-ray

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

How does alveolar oedema present on chest X-ray and what is it indicative of?

A

Appears as fluffy white surrounding black tubes in the lungs and is a late sign of heart failure

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

In which condition would the loss of costophrenic angles be seen on chest X-ray?

A

Pleural effusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the definition of myocardial infarction?

A

Elevated troponin in a clinical setting consistent with myocardial ischaemia

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What is the difference between type 1 and type 2 MI?

A

Type 1 is due to plaque rupture and thrombus formation
whereas
Type 2 is due to increased oxygen demand or decreased oxygen supply

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Describe unstable angina

A

An acute coronary event without a rise in troponin

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What does ST elevation in MI indicate?

A

Coronary artery occlusion

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Name the three types of atrial fibrillation in order of increasing duration?

A

Paroxysmal
Peristsent
Permanent

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Name the two main features of AF on an ECG

A

Narrow, irregular QRS complex

No P waves

17
Q

Subclinical thyrotoxicosis can cause which heart arrhythmia?

A

Atrial fibrillation

18
Q

Describe the mechanism of action of Verapamil

A

Acts on Ca channels in the heart muscle to slow heart rate

19
Q

Name three components of vegetation which can go onto damage cusps of heart valves

A
Any three of:
Fibrin mesh 
Platelets 
WBCs
RBC debris 
Trapped organisms
20
Q

Strep. viridans is commonly associated with what type of endocarditis?

A

Native valve endocarditis

21
Q

Which strain of bacteria is commonly found in endocarditis of IVDU?

A

Staphylococcus aureus

22
Q

What are the two main categories of late stage infection in endocarditis?

A

Immunological and tissue damage

23
Q

In foetal circulation, via which structure does blood pass from the IVC to the left atrium?

A

Foramen Ovale

24
Q

Which term describes a heart with normal anatomy in a normal anatomical position?

A

Situs solitus

25
Q

In Fontan circulation, what adaptations are made in order to allow perfusion of blood?

A

IVC and SVC are plumbed directly into the pulmonary arteries, allowing bypassing of the heart

26
Q

What measurement defines systemic hypertension?

A

BP over 140/90mmHg

27
Q

Name three potential causes of secondary hypertension

A

Hyperaldosteronism
Coarctation of aorta
NSAIDs

28
Q

What is the first line treatment for under 55s with hypertension?

A

ACE inhibitor or low-cost angiotensin II receptor blocker