Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

INT 208: Pharmacology > Cardiac Dysrhythmia > Flashcards

Cardiac Dysrhythmia Flashcards

1
Q

Class IA anti-Arrhythmic drugs Mechanism

A

Block Both Sodium & Calcium channels:
* Slows Phase 0 –> slow Excitability & Conductivity
* Slow Phase 4 –> Low Automaticity
* Long Phase 3 –> Long Action potential duration & Refractory Period

Affects all, thus broad spectrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Enumerate Class IA anti-Arrhythmic drugs

A
  • Quinidine
  • Procainamide
  • Disopyramide
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Uses of Class IA anti-Arrhythmic drugs

A
  • Atrial Fibrillation
  • Ventricular tachycardia
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Class IB anti-Arrhythmic drugs Mechanism

A

Blockes Inactivated Na+ channels —> low Phase 4 —> Low Automaticity

  • No effect on conductivity (AVN)
  • Not effective in Atrial fibrillation (Narrow spectrum)
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

enumerate Class IB anti-Arrhythmic drugs

A
  • Lidocane
  • Phenytoin
  • Mexiletine
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Uses of Lidocane (Class IB)

A
  1. Emergency ventricular arrhythmia without heart block
  2. Myocardial infarction
  3. Digitalis induced arrhythmia
  4. Local & General Anesthetic
  5. Cardiosurgeoury or Catheter
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What to consider when giving Lidocane

A

decrease its dose in liver disease & drugs lowering hepatic blood flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

the only Class IB drug can be used in Ventricular Arrhythmia with heart block

A

Phentoyin (may decrease AV conduction)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Class IC anti-Arrhythmic drugs Mechanism

A

Block Activated Na+ channels —> Slow phase 0 —> slow Excitability & conductivity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

Class IC anti-Arrhythmic drugs Example

A
  • Flecainide
  • Encainide
  • Propafenone
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

Contraindication of Flecainide/Encainide/propafenone

A
  • Heart failure
  • left ventricular Hypertrophy
  • CHD

Beta blocking, negative inotropic, pro arrhythmic

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

uses of Flecainide/Encainide/propafenone (Class IC)

A
  • Atrial fibrillation
  • Ventricular tachycardia

broad spectrum

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

Class II anti-Arrhythmic drugs Mechanism

A

Beta blockers:
* depress all Cardiac properties

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Enumerate Class II anti-Arrhythmic drugs

A

Beta blockers:
* Esmolol
* propranolol
* Atenolol
* Metoprolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Class II anti-Arrhythmic drug reducing risk of bronchospasm (most widely used)

A

Metoprolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Class II anti-Arrhythmic drug used in Acute arrhythmia emergency and is metabolised by RBCs

A

Esmolol

17
Q

Mechanism of action of Class III anti-Arrhythmic drugs

A

K+ Channel blockers –> Long Phas 3 –> long refractory period & Period of depolarization

18
Q

Enumerate Class III anti-Arrhythmic drugs

A
  • Amiodarone
  • Dronedarone (less side effects than amiodarone)
  • Bretylium
  • Sotalol (actually beta blocker)
19
Q

which class II drug belongs to Class III

A

Sotalol

20
Q

Uses of Amiodarone

A

Severe & refractory supraventricular & ventricular arrhythmia

21
Q

Adverse effects of Amiodarone

A
  • Pulomary inflammation & fibrosis
  • Thyroid dysfunction
  • skin discoloration
  • corneal deposits
22
Q

Enumerate Class IV anti-Arrhythmic drugs

A

calcium channel blockers:
* Verapamil
* Diltiazem

23
Q

uses of Class IV anti-Arrhythmic drugs

A
  • reentrant supraventriuclar tachycadia
  • decrease ventricular rate in Atrial flutter & fibrillation
24
Q

Drug of choice in Atrial flutter/Fibrillation

A

Digoxin

25
Q

Drug of choice in Superaventricular tachycardia

A
  • Adenosine
  • Verpamil (class IV ca2+ blocker)
26
Q

drug of choice in Sustained ventricular tachycardia

A

Lidocane

27
Q

drug of choice in Ventricular Fibrillation

A

Lidocane

28
Q

drug of choice in Digitalis induce ventricular tachycardia

A

Lidocane

29
Q

Drug of choice in Torse De pointes

A

Magnesium

INT 208: Pharmacology (30 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions