Carcinogenesis part 2

Question 1

What is cancer cachexia?

Answer 1

1. Equal loss of body fat and lean muscle mass

2. Elevated basal metabolic rate

Question 2

Discuss the tumor grading system

Answer 2

Stage 1: Well-differentiated
Stage 2: Moderately differentiated
Stage 3: Poorly differentiated
Stage 4: Anaplastic

Question 3

Describe Immunohistochemistry

Answer 3

Identifies cellular elements or surfac markers by using specific monoclonal antibodies. Useful for categorizing undifferentiated cancers and determining the origin of metastatic cancer.

Question 4

Describe Flow Cytometry

Answer 4

Measure several cell surface markers. Used to diagnose leukemia and lymphoma.