Cancer Flashcards

1
Q

Describe mitosis

A

Is division of a somatic cell that results in 2 identical daughter cells.

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2
Q

Stages of mitosis

A

G1- interphase where cell DNA is copied
S- 46 chromosomes are dublicated
G2- cell doubble checks for any errors
mitosis- cells are expelled.

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3
Q

The cell has a variation of size and shape, the nucli is rapid and abnormal what is this?

A

Cancerous cell

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4
Q

Define cancer

A

Abnormal cell regulation where the function of cell production becomes abnormal and unpredictable.

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5
Q

Benign

A

Harmless and does not require intervention

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6
Q

Maliginant

A

Indicates cancer and can be harrmfull with no intervention

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7
Q

what is metastasis

A

ability to spread

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8
Q

what is proliferation

A

uncontrolled growth

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9
Q

what does carcinoma mean

A

maliginant tumour of epithelial organ

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10
Q

neoplasm

A

newly formed tumour

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11
Q

most common cancer in both genders?

A

Lung

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12
Q

Causes of cancer

A
Sunlight
smoking
obeasity
high fat diet
infections: HPV, Epstein Bar
Alcohol
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13
Q

Explain the grading for cancer T grading in an example o the bowel

A

T1- bowel tissue only
T2- Grown into the muscular layer of bowel
T3- Has grown through muscle into the outer tissues
T4- Has grown to surrounding organs such as liver

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14
Q

Explain the grading for cancer N grading

A

N0- No lymph node involvment
N1- 1 to 3 lymph nodes surrounding the tissue contain cancer
N2- 4 or more cancer cells grown more than 3cm away from the tumour and are connected to blood supply vessels around the body

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15
Q

Explain the grading for matesis

A

M0- Has not spread to other organs

M1- tumours have spread to other organs in body

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16
Q

which organs prolifferate quickly?

A

Bone marrow, Overies, testisies, hair follicles, bowel mucosa

17
Q

which organs prolifferate slowly?

A

Lung, liver, kidneys, endocrine glands, vascular

18
Q

Cancer diagnosis?

A
History
Physical exam 
X-ray 
Blood tests 
CT scan 
MRI  
sputle sample
scope
biopsy
mammogram 
smear
19
Q

side effects of radiotherapy to head and neck?

A
hair loss
dry mouth 
dificulty swallowing
blistering 
no voice
dry eyes
cerebral oedema
nausea/vomiting
rash
20
Q

What interventions are appropriate for a head and neck radio patient?

A
Mouth- care kit
dental extractions
skin care 
analgesia 
anti-emetics
eye drops
21
Q

Thoratic radiation side effects?

A
Skin Rash 
Osophogitis 
dysphagia
cough 
wheeze
late pulmonary fibrosis 
pain 
nausea/ fatigue 
dysapnea
22
Q

Nursing care for radiation to the thoratic cage?

A
skin care/ avoidance of wires in bras
nutritional assessment little and often 
positioning/ oxygen and nebulisers
analgesia
codine
rest
warm fluids
23
Q

Abdomnal radiation side effects

A
dihorrea
constipation 
anal ulceration
pain
tenesmus (sensation to open the bowels)
cystitis/haematuria
loss of erectile function
discharge 
dryness
vaginitis
24
Q

abdominal radiation nursing interventions

A
skin care
management for bowels (movicol, laperomide)
increase fluid intake
lubricant 
consider egg/sperm freezing
immunosupression
25
Q

what is brachytherapy?

A

grains of radiotherapy inserted into the cancerious area to expose radiation

26
Q

what is radioactive isotope therapy?

A

procedure in which a liquid form of radiation is administered internally through infusion or injection.

27
Q

what are targeted therapy (monocolnial antibodies?)

A

They target the protein in the cells causing them to die or trigger the immune system to attack the cells.

28
Q

How does hormone therapy work?

A

slows down or prevents the cancer from growing

29
Q

why is chemo given on certain dates?

A

To target the cell cycle at its most vunerable.

30
Q

what differet routes can you give chemo?

A

orally
intravenously
catheter
intracavity

31
Q

side effects of chemotherapy?

A
nausea/ vommiting
Hair loss
lethargy 
immunosuppression 
dry/ sore skin
change in bowel habbit 
psychological/ emotional impact 
death
32
Q

what types of groups of chemotherapy are there?

A

anti-metabolisers: inhibit proteins and enzymes for DNA production
Alkylating agents: stop the DNA from unravveling
cytoxic antibodies: stop the DNA replication
plant alkaloids: stop the spindle from forming

33
Q

Other uses of chemotherapy?

A

Rhumatoid arthritis
chrones disease
psorisis
vasculitis