Cancer Flashcards
Cancer Stats
40% of Americans in their lifetime; nearly two-thirds of cancer survivors live for at least five years, not the leading cause of death, second behind heart disease
Causes of Cancer
Tobacco, obesity, diet, lack of exercise, occupation, viruses, family history, alcohol, UV and ionizing radiation, prescription drugs, reproductive factors, pollution, unknown
Physical activity reduces risk of colorectal cancer by up to 50%, obesity and physical inactivity increase risk of breast cancer in women by 50%
Pathophysiology of Cancer
A disease in which abnormal cells divide uncontrollably and destroy body tissue
- results from DNA damage form internal or environmental factors
- has potential to for metastasis
Carcinoma:
from epithelial tissues, most common (lung, colon, prostate, breast)
Sarcoma
from connective tissues like bone, fat, cartilage, nerves
Leukemia and lymphoma
from blood forming cells called hematopoietic cells
Development of Cancer
Normal tissue undergoes a progression of abnormal changes from hyperplasia (increase in number of cells but cells still appear normal under a microscope)
then dysplasia occurs (where cells look abnormal)
then cancer
Treatment/Management of Cancer
Medications
Chemo
Radiation Therapy: damage DNA of cancerous tissue
Surgery: primary method, remove the tumor
Hormone Therapy
Targeted Therapies( form of chemo): targets specific molecular differences between cancer and normal cells
Exercise: overall physical function is generally diminished because of losses of aerobic capacity, muscle tissue and ROM
Exercise Response (cancer)depends on
Tumor site, cancer stage, grade, treatment, timing since diagnosis and interactions of all elements with general health, well being and fitness
Medical Assessments before exercise
Recommend evaluation for peripheral neuropathies, musculoskeletal morbidities
If the patient has hormonal therapy it could lead to fracture risk
Breast Cancer Evaluation
Arm/shoulder morbidity to upper body exercise
Prostate Cancer Eval
Evaluation of muscle strength and wasting
Colon Cancer Eval
Eval patient as having established consistent and proactive infection prevention behaviors for an existing ostomy prior to engaging in exercise training that is more vigorous than a walking program
Gynecologic Cancer Eval
Patients that are morbidly obese may require additional medical assessment for the safety of activity beyond cancer-specific risk. Eval the lower extremity lymphedema prior to vigorous aerobic exercise or resistance training
Recommendation for Exercise Testing Cancer (High functioning)
an exercise test to establish current baseline and determine if treatments affected exercise response is useful
Recommendation for Exercise Testing Cancer (Low functioning)
an exercise test might provide a barrier to physical activity
Exercise Testing (general concepts)
No assessment required to start a light, walking progressive strength training, or flexibility program in survivors
Be aware of a survivors health history, comorbid chronic health conditions and diseases, and any exercise contraindications
Ideally patients with cancer should receive a comprehensive assessment