Cancer

Question 1

neuroblastoma primary site/originate

Answer 1

abdomen
originate from embryonic neural crest cells; arise out of *sympathetic nervous system and adrenal medulla
right above the adrenal gland

Question 2

neuroblastoma presentation

Answer 2

can feel irregular mass in the abdomen
will crossover abdomen - can feel on both sides
generally encapsalate - can metastisize

Question 3

s/s of neuroblastoma

Answer 3

flushing/sweating
tachycardia
htn

Question 4

wilms tumor (nephroblastoma) site/originate

Answer 4

abdomen - generally stays to one side

originate from renal parenchyma from renoblast cells - grows on the kidney

Question 5

wilms tumor associated w/other congenital abnormalities

Answer 5

undestended testes
hytrophy - unsymmetrical - one side lgr. than other
dont have an iris
cardiac malformations

Question 6

**wilms tumor avoid

Answer 6

palpating abdomen - causes seeding; metastasis

Question 7

ewings sarcoma (primitive neuroectodermal tumor of the bone) site/originate

Answer 7

occurs in long bones and trunk bones

arises in bone marrow-marrow spaces of the bone (appears moth eaten on xray)

Question 8

osteosarcoma site/originate

Answer 8

bone-forming mesenchyme giving rise to malignant osteoid tissue

Question 9

osteosarcomas give rise to

Answer 9

cancer tissues which can metastasize to lungs

Question 10

with osteosarcomas distinguish between

Answer 10

ewing or osteo sarcoma

Question 11

onset for osteosarcoma

Answer 11

adolescence or above- teen-25 y.o. is greatest incidence

Question 12

ewing sarcoma onset

Answer 12

younger aged children

Question 13

retinoblastoma is found in

Answer 13

retinal tumor - usually in one eye

Question 14

retinoblastoma can run in a family t or f

Answer 14

true; can be spontaneous

Question 15

s/s of retinoblastoma

Answer 15

cat eye reflex -whitish glow appearance of pupil