Cahapter 12: DNA Flashcards

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1
Q

Adenine

A

(A) a compound which is one of the four constituent bases of nucleic acids. A purine derivative, it is paired with thymine in double-stranded DNA.

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2
Q

Bacteriophage

A

a virus that parasitizes a bacterium by infecting it and reproducing inside it.

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3
Q

Base

A

The nucleobase of a nucleotide involved in base pairing, as of a DNA or RNA polymer

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4
Q

Complementary Base Pair

A

the phenomenon where in DNA guanine always hydrogen bonds to cytosine and adenine always binds to thymine.

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5
Q

Cytosine

A

(C) a compound found in living tissue as a constituent base of nucleic acids. It is paired with guanine in double-stranded DNA.

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6
Q

Deletion Mutation

A

a mutation in which a part of a chromosome or a sequence of DNA is lost during DNA replication. Any number of nucleotides can be deleted, from a single base to an entire piece of chromosome.

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7
Q

DNA Helicase

A

are essential during DNA replication because they separate double-stranded DNA into single strands allowing each strand to be copied.

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8
Q

DNA Ligase

A

a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.

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9
Q

DNA Polymerase

A

an enzyme that synthesizes DNA molecules from deoxyribonucleotides, the building blocks of DNA. These enzymes are essential for DNA replication and usually work in pairs to create two identical DNA strands from a single original DNA molecule.

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10
Q

DNA Replication

A

is the process by which DNA makes a copy of itself during cell division. The first step in DNA replication is to ‘unzip’ the double helix structure of the DNA molecule

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11
Q

Double Helix

A

a pair of parallel helices intertwined about a common axis, especially that in the structure of the DNA molecule.

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12
Q

Free Nucleotide

A

A free, unincorporated nucleotide usually exists in a triphosphate form; that is, it contains a chain of three phosphates. … In this manner, each strand of DNA has a “backbone” of phosphate-sugar-phosphate-sugar-phosphate

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13
Q

Guanine

A

(G) one of the four constituent bases of nucleic acids. A purine derivative, it is paired with cytosine in double-stranded DNA.

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14
Q

Insertion Mutation

A

the addition of one or more nucleotide base pairs into a DNA sequence

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15
Q

Inversion

A

a chromosome rearrangement in which a segment of a chromosome is reversed end to end. An inversion occurs when a single chromosome undergoes breakage and rearrangement within itself

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16
Q

Mutation

A

he alteration of the nucleotide sequence of the genome of an organism, virus, or extrachromosomal DNA.

17
Q

Nucleotide

A

a compound consisting of a nucleoside linked to a phosphate group. Nucleotides form the basic structural unit of nucleic acids such as DNA.

18
Q

Nucleotide Substitution Mutation

A

a single nucleotide base is changed, inserted or deleted from a sequence

19
Q

Semiconservative Replication

A

the mechanism of DNA replication in all known cells. t produces two copies of the original DNA molecule, each of which contains one of original strand, and one newly-synthesized strand.

20
Q

Sugar-Phosphate Backbone

A

an important stuctural component of DNA. It consists of 5-carbon deoxyribose sugars and phosphate groups

21
Q

Thymine

A

a compound which is one of the four constituent bases of nucleic acids. A pyrimidine derivative, it is paired with adenine in double-stranded DNA.

22
Q

Translocation

A

a phenomenon that results in unusual rearrangement of chromosomes.