Cahapter 12: DNA Flashcards
Adenine
(A) a compound which is one of the four constituent bases of nucleic acids. A purine derivative, it is paired with thymine in double-stranded DNA.
Bacteriophage
a virus that parasitizes a bacterium by infecting it and reproducing inside it.
Base
The nucleobase of a nucleotide involved in base pairing, as of a DNA or RNA polymer
Complementary Base Pair
the phenomenon where in DNA guanine always hydrogen bonds to cytosine and adenine always binds to thymine.
Cytosine
(C) a compound found in living tissue as a constituent base of nucleic acids. It is paired with guanine in double-stranded DNA.
Deletion Mutation
a mutation in which a part of a chromosome or a sequence of DNA is lost during DNA replication. Any number of nucleotides can be deleted, from a single base to an entire piece of chromosome.
DNA Helicase
are essential during DNA replication because they separate double-stranded DNA into single strands allowing each strand to be copied.
DNA Ligase
a specific type of enzyme, a ligase, that facilitates the joining of DNA strands together by catalyzing the formation of a phosphodiester bond.
DNA Polymerase
an enzyme that synthesizes DNA molecules from deoxyribonucleotides, the building blocks of DNA. These enzymes are essential for DNA replication and usually work in pairs to create two identical DNA strands from a single original DNA molecule.
DNA Replication
is the process by which DNA makes a copy of itself during cell division. The first step in DNA replication is to ‘unzip’ the double helix structure of the DNA molecule
Double Helix
a pair of parallel helices intertwined about a common axis, especially that in the structure of the DNA molecule.
Free Nucleotide
A free, unincorporated nucleotide usually exists in a triphosphate form; that is, it contains a chain of three phosphates. … In this manner, each strand of DNA has a “backbone” of phosphate-sugar-phosphate-sugar-phosphate
Guanine
(G) one of the four constituent bases of nucleic acids. A purine derivative, it is paired with cytosine in double-stranded DNA.
Insertion Mutation
the addition of one or more nucleotide base pairs into a DNA sequence
Inversion
a chromosome rearrangement in which a segment of a chromosome is reversed end to end. An inversion occurs when a single chromosome undergoes breakage and rearrangement within itself