brain learning and motivation: brain behaviour- genetics Flashcards
mendalean genetics
19th century monk
demonstrated inheritance occurs through genes
• Genes are aligned along chromosomes (strands of genes) and come in pairs
• A gene is a por1on of a chromosome and is composed of deoxyribonucleic acid (DNA)
DNA
serves as a model for the synthesis of ribonucleic acid (RNA)
RNA
is a single strand chemical that can serve as a template/ model for the synthesis of proteins
proteins
determine the development of the body by:
Forming part of the structure of the body
Serving as enzymes, biological catalysts that
regulate chemical reac1ons in the body
homozygous for a gene
means that a person has an iden1cal pair of genes on the two chromosomes
heterozygous for a gene
means that a person has an unmatched pair of genes on the two chromosomes
how many genes control a characteristic
not just one
– Eye colour: at least 10 genes (Liu et al, 2010) – Height: at least 180 genes (Alen et al, 2010)
gene expression
• Some genes are only expressed partly: in some cells and not others or only under certain circumstances
types of genes
autosomal: all genes except for sex linked
sex linked genes: located on sex chromosomes
human x chromosome
has genes for approx 15000 proteins
sexlinked characteristics
usually refer to those on x chromosome e.g. red green colour blindness
genes change in several ways…
mutation
microduplication
microdeletion
mutation
a heritable change in a DNA molecule
microduplication/microdeletion
part of a chromosome that might appear once might appear twice or not at all
epigenetics
a field that is concerned with changes in gene expression without the modifica1on of the DNA sequence
Epigene1c differences are a likely explana1on for differences between monozygo1c “iden1cal” twins
gene activity
some genes are only active at specific times in ones life or during the day
eg a malnourished mother would have pups who would easily consev energy but this could lead to obesity in the pups
how experiences alter the activity of genes
What you do at any moment not only affects you now, but produces epigene1c effects that alter gene expressions for a longer period of 1me
heredity and environment
- Almost all behaviors have both a gene1c component and an environmental component
- Researchers study monozygo1c (“from one egg”) and fraternal (“from two eggs”) twins to infer contribu1ons of heredity and environment
- Researchers also study adopted children and their resemblance to their biological parents to infer hereditary influences
enviromental factors influence Schizophrenia
in those at risk of developing Schizophrenia, environmental factors such as stress influences its development
Study of predisposed adopted children in psychologically healthy families vs. adopted children with families that were disturbed
In healthy families, none became psycho1c
In disturbed families, 11 percent of the children became psycho1c and 41 percent had severe psychological disorders
heritability
refers to how much characteris1cs depend on gene1c differences
Researchers have found evidence for heritability in almost every behavior they have tested
• Heritability of a certain trait is specific to a given popula1on
• Strong environmental influences may cause gene1c influences to have less of an effect
Traits with a strong hereditary influence
by modified by environmental interven1on
– e.g., PKU: a gene1c inability to metabolize the amino acid phenylketonuria
– Environmental interven1ons (a special diet) can modify PKU
how genes influence behaviour
genes don’t directly influence behaviour
heredity and environment
Genes produce proteins that increase the probability that a behavior will develop under certain circumstances
• Genes can also have an indirect affect
– Genes can alter your environment by producing behaviors or traits that alter how people in your environment react to you
the evolution of behaviour
Evolu1on refers to a change in the frequency of various genes in a popula1on over genera1ons
regardless if the characteristic is helpful or harmful to the population
evolution attempts to answer two questions
– How did some species evolve?
– How do species evolve?
how species did evolve
involves the tentative production of evolutionary trees
how species do evolve
rests upon these assumptions:
Offspring generally resemble their parents for gene1c reasons
– Muta1ons, recombina1on, and microduplica1ons of genes introduce new heritable varia1ons
– Certain individuals successfully reproduce more than others do
artificial selection
refers to:
choosing individuals with desired traits and making them parents of the next genera1on
natural selection
According to Darwin, nature also selects, and successful individuals’ genes will be prevalent in later genera1ons
common misconceptions about evolution:
– Lamarckian evolu1on: “The use or disuse of some structure or behavior causes an increase or decrease in that structure/behavior.”
– “Humans have stopped evolving.”
– “Evolu1on means improvement.”
– “Evolu1on acts to benefit the individual or the species.”
evolutionary psychology
focusses upon
func1onal and evolu1onary explana1ons of how behaviors evolved
assumes that:
Assumes that behaviors characteris1c of a species have arisen through natural selec1on and provide a survival advantage
Altruistic behaviour
describes behaviour that benefits one individual a lot more than another
hard to find altruism outside of humans
group selection
is a controversial hypothesis that states that altruis1c groups survive beUer than less coopera1ve ones
kin selection
the favored explana1on: selec1on for a gene that benefit’s the individual’s rela1ves
comparative psychology
the use of animals to study behaviour and the brain
comparative psychology: animal research
has told us most o what we know about the nervous system
though poses an ethical dilemma
reasons for animal research
the underlying mechanisms of behaviour are similar across species and often easier to stud in non-human species
information learned form animals sheds light on human evolution
tells us about animal evolution swell
some experiments cannot use humans for legal or ethical reasons
examples of animal research
squid axons: human axons are too small
visual cortex in the cat
Pleasure centres in the brain and dopamine