Bovine-Respiratory Pathology

Question 1

Fibrinonecrotic rhinitis is classic for

Answer 1

IBR (BHV-1)

-also malignant catarrhal fever

Question 2

IBR disease complexes

Answer 2

1. rhinotracheitis and bronchointerstitial pneumonia
2. systemic infectious dz young calves
3. pustular vulvovaginitis/balanoposthitis
4. Abortion - 5 mos
5. Encephalitis (BHV-5)
6. Latency reactivation trigeminal ganglia

Question 3

Other gross lesions MCF

Answer 3

1. Lymphadenomegaly
2. Panophthalmitis
3. Oral, esophageal, stomach ulcerations
   - can see in IBR
4. Nephritis
5. Cystitis

Question 4

Classic histophilus lesion feedlot cattle

Answer 4

septic infarcts in larynx

Question 5

Necrotizing laryngitis DDX

Answer 5

1. Laryngeal contact ulcers - forced resp efforts
2. Necrobacillosis - after initial injury
3. Histophilus - septic infarct larynx

Question 6

Morphologic patterns pneumonia

Answer 6

1. Bronchopneumonia
   - cranial ventral, bacteria or aspiration
2. Interstitial
   - diffuse/locally extensive, toxin, virus, fungus, prot.
   - thick interalveolar septum
3. Multifocal pneumonia
   - 2 to hematogenous spread bacteria, fungi, other infect
4. Mixed bronchointerstitial

Question 7

Pastuerellosis, Bovine resp dz complex

Answer 7

1. Enzootic pneumonia

2. pasteurellosis/mannheimiosis

Question 8

Sequelae to chronic bronchopneumonia

Answer 8

1. Bronchiectasis
2. Pleural fibrosis
3. Bronchiolitis obliterans
4. Pulmonary abscesses
5. Big lymph nodes

Question 9

Pulmonary abscesses DDX

Answer 9

1. Truperella
2. Pasteurella multocida
3. Tuberculosis

Question 10

Mycoplasma mycoides mycoides syndrome

Answer 10

Contagious bovine pleuropneumonia

• fibrinous pleuritis
• arthritis
• granulomatous pneumonia

Question 11

Vessel calcification seen in

Answer 11

tuberculosis, not mycoplasmosis

Question 12

Gross lesions mycobacterium bovis (tuberculosis)

Answer 12

1. Granulomatous pneumonia
2. Granulomatous lymphadenitis: head and neck LNs
3. Granulomas spleen, liver, intestine

Question 13

Definitive dx tuberculosis

Answer 13

Culture and PCR of gross lesions

Question 14

Miscellaneous causes of pneumonias and bronchitis in cattle

Answer 14

1. Bacterial Septicemia
2. Fungal infection
3. Dictyocaulis viviparous

Question 15

Dictyocaulis viviparous

Answer 15

1. Cattle ingest L3
2. L3 migrate via intestine and lymphatics
3. L3 to L4 in mesenteric lymph nodes
4. L4 reach lung develop to L5 (adult) in airways
5. Eggs with L1 swallowed, passed in feces
6. L2-L3 in feces/pasture

Question 16

Bovine atypical interstitial pneumonia

Answer 16

Infectious
1. Lungworms
2. BRSV-one report
Toxic
1. 3-methylindole
2. 4-ipomeanol
3. perilla ketone
4. Brassica sp
-kale
-rape
-turnup tops

Question 17

Toxic interstitial pneuonias in cattle

Answer 17

1. L-tryptophan/3-methylindole
   - Acute bovine pulmonary edema and emphysema
   - Fog Fever; change to lush pasture
2. 4-ipomeanol (mostly sweet potatoes)
   - Fusarium solani
3. Perilla ketone
   - 3-substituted furan similar to 4-ipimeanol
4. Stinkwood (ziera arborescens)
5. Rapeseed and kale

Question 18

Pulmonary edema think

Answer 18

L-tryptophan (fog fever)

Question 19

Fibrinous pneumonia think

Answer 19

Malignant catarrhal fever (Ovine herpesvirus)