Bovine-lymphoid pathology

Question 1

Lymphoma in cattle

Answer 1

1. Relatively common (18/100,000)
2. Most forms caused by BLV
3. Persistent lymphocytosis in 30% BLV infected cattle

Question 2

Anatomic distribution lymphoma in cattle

Answer 2

1. Multicentric - most common BLV association
2. Cutaneous
3. Thymic - adolescent, bone marrow involv
4. Calf form - dramatic
5. Alimentary - rare

Question 3

Calf form lymphoma

Answer 3

1. less than 6 months old
2. generalized nodes, bone marrow, blood, liver, spleen
3. 50% involve thymus, heart, kidneys, uterus
4. bone involvement may lead to pathologic fractures

Question 4

Common places lymphoma

Answer 4

1. abomasum
2. R. atrium
3. Uterus/vagina/ovary

Question 5

Hairy vetch tox

Answer 5

Toxic component unknown, possibly hypersensitivity

Usually affects cattle > 3 yrs old

Question 6

Forms hairy vetch tox

Answer 6

1. Acute nervous form
2. Herpetiform oral lesion
3. Dermatitis, conjunctivitis, diarrhea with systemic granulomatous dz
   - skin, heart, adrenal, kidney, lymphoid tissues

Question 7

Citrus pulp toxicity

Answer 7

1. fed in ration up to 20%, unpredictable
2. granulomatous lesions
   - LNs, liver, spleen, heart, pancreas, adrenal, intestines
3. unknown toxic principle
   - lectin, hypersensitivity?

Question 8

Chronic granulomatous splenitis

Answer 8

HUGE SPLEEN

-citrus pulp toxicity