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NPLEX2 Botanicals > Botanicals musculoskeletal system > Flashcards

Botanicals musculoskeletal system Flashcards

1
Q

How many MSK botanicals? name them

A
  1. Arnica montana
  2. Boswellia serrata
  3. Byronia alba
  4. Byronia cretica dioca
  5. Herpagophytum procumbens
  6. Piper methysticum
  7. Salix alba
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2
Q

Arnica montana (arnica) constituents

A

Sesquiterpene lactones (helenalin), folavonoids, polysaccharides, volatile oil (thymol)

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3
Q

Arnica montana (arnica) actions

A

Topical anti-inflammatory, vulnerary, immune stimulant

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4
Q

Arnica montana (arnica) pharmacology

A

Arnica has immunostimulating properties as both sesquiterpenme lacotone helenalin and polysaccharide fraction stimulate phagocytosis. Helenalin has anti-inflammatory activity mediated through immunological processes.

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5
Q

Arnica montana (arnica) indications

A

Topical: bruises, phlebitis, rheumatism, strains, and sprains, myalgia

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6
Q

Arnica montana (arnica) s/e

A

May cause contact/allergic dermatitis (sesquiterpene lactones) when applied topically

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7
Q

Arnica montana (arnica) CI

A

Internal use, broken skin, and allergy or hypersenstivity to asteraceae family

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8
Q

Arnica montana (arnica) interactions

A

N/a

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9
Q

Bosweilia serratoa (Frankincense) constituents

A

Resins: boswelic acid; volatile oils, water soluble gum

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10
Q

Bosweilia serratoa (Frankincense) actions

A

Anti-inflammatory, circulatory stimulant. Analgesic, antiseptic, astringent

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11
Q

Bosweilia serratoa (Frankincense) indications

A

Asthma, Crohn’s, ulcerative colitis, OA, RA, chronic prostatitis, inflammation

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12
Q

Bosweilia serratoa (Frankincense) s/e

A

G.I. irritation or pain. Take with water or food

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13
Q

Bosweilia serratoa (Frankincense) CI

A

N/a

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14
Q

Bosweilia serratoa (Frankincense) interactions

A

Enhances NSAIDS – aspirin, ibuprofen, naproxen, celecoxib

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15
Q

Byronia alba (white bryony) and Bryonia crtica dioica (Red bryony) constituents

A

Cucurbitacins, polyhydroxy fatty acids, volatile oils, tannins

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16
Q

Byronia alba (white bryony) and Bryonia crtica dioica (Red bryony) pharmacology

A

Curcubitanes have strong toxic and cytotoxic a fact. Topical application is irritating to the skin and mucous membranes. Aqueous extracts display antitumoral effect in animal studies. The resin is a drastic purgative. Use of this herb as a purgative has been obsolete due to toxicity.

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17
Q

Byronia alba (white bryony) and Bryonia crtica dioica (Red bryony) actions

A

Anodyne, sedative, anti-rheumatic, anti-viral, cathartic

18
Q

Byronia alba (white bryony) and Bryonia crtica dioica (Red bryony) indications

A

Painful rheumatism, either internally or as a counter irritant. ByRonia has been used as a laxative, emetic and diuretic for various disorders of the G.I. and respiratory tract – doudenal ulcers, asthma, bronchitis.

19
Q

Byronia alba (white bryony) and Bryonia crtica dioica (Red bryony) s/e

A

Contact between the skin and the juice of the plant can lead to rash, infection, blister formation and necrosis. Overdosage can lead to vomiting, bloody diarrhea, colic, collapse, paralysis. 40 berries would lead to death in adult, 15 for a child.

20
Q

Byronia alba (white bryony) and Bryonia crtica dioica (Red bryony) CI

A

Pregnancy and lactation, generally not for internal use

21
Q

Byronia alba (white bryony) and Bryonia crtica dioica (Red bryony) interactions

A

n/a

22
Q

Harpagophytum procumbens (Devil’s claw) constituents

A

Iridoid glycosides: harpagoside. Flavonoids, phenolic acids,phytosterols

23
Q

Harpagophytum procumbens (Devil’s claw) actions

A

Anti-inflammatory, anti-rheumatic, anodyne, analgesic. Bitter, digestive stimulant; hepatic

24
Q

Harpagophytum procumbens (Devil’s claw) indications

A

Arthritis (harpogoside), tendonitis. Dyspepsia, lack of appetite, liver and GB compications

25
Q

Harpagophytum procumbens (Devil’s claw) s/e

A

N/a

26
Q

Harpagophytum procumbens (Devil’s claw) CI

A

Stomach or duodenal ulcers d/t the herb’s stimulation of gastric juice secretion

27
Q

Harpagophytum procumbens (Devil’s claw) interactions

A

Incompatible with drugs intended to reduce gastric acid secretion due to bitter action. Decreases need for NSAIDS and other analgesics and osteoarthritis and low back pain.

28
Q

Piper methysticum (Kava kava) constituents

A

Kava lactones (kava pyrones); kavain, dihydrokavain, methysticin, yangonine, dihydromethysticin

29
Q

Piper methysticum (Kava kava) pharmacology

A

Kava’s analgesic affect is due to inhibition of COX enzyme-II. The analgesic action of Kavain, dihydrokavain, methysticin and dihydromethsticin is due to antinociceptive activities. Kava pyrones inhibit the limbic system that can affect mild generalized anxiety disorder, but not moderate to sever anxiety. Kava pyrones inhibit sodium ions currents giving it muscle-relaxant properties.

30
Q

Piper methysticum (Kava kava) actions

A

Skeletal muscle relaxant, antispasmodic; sedative, anxiolytic

31
Q

Piper methysticum (Kava kava) indications

A

Nervous anxiety and stress; Russell sniffs, tension and agitation. Neuralgia (facial, trigeminal, toothache).

32
Q

Piper methysticum (Kava kava) s/e

A

Apple toxicity, additive, exfoliative dermatitis, ulcers, vomiting, unconsciousness

33
Q

Piper methysticum (Kava kava) CI

A

Kavalactones enter breast milk. Not to be used during pregnancy. Kava is CI in patients with endogenous depression b/c it may increase the danger of suicide

34
Q

Piper methysticum (Kava kava) Interactions

A

Potentiates anti-psychotics (risperidone), benzodiazepines (alprazolam, diazepam)

35
Q

Salix alba (White willow) Constituents

A

Phenolic glycosides (salicin, salicyclic acid), flavonoids, tannins, catechin

36
Q

Salix alba (White willow) actions

A

analgesic, anti-inflammatory, febrifuge, anti-rheumatic

37
Q

Salix alba (White willow) indications

A

Rheumatism, gout, fevers, aches and pains. Menstrual pain, sweating, hot flashes

38
Q

Salix alba (White willow) s/e

A

Salicylism: n/v (d/t tannin content), GI irritation, tinnitus, lethargy, dizziness, cerebral edema, seizures

39
Q

Salix alba (White willow) CI

A

Salicylates should not be used in children with flu like symptoms to do the association of salicylates with a reye’s syndrome. Salicylate sensitivity, glucose six phosphate dehydrogenase deficiency, pregnancy, lactation, long-term use

40
Q

Salix alba (White willow) Interactions

A

May potentiate acetaminophen and NSAIDS – aspirin, ibuprofen, naproxen, celecoxib, anticoagulants – warfarin. Do not use as a substitute for aspirin if blood thinning action is required

NPLEX2 Botanicals (12 decks)

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