Botanicals immune system Flashcards
What are the 3 categories of botanicals for the immune system. How many botanical are there? Can you name them?
26 Botanicals in all
Infection:
- Artemisia annua
- Baptisia tinctoria
- Cinnamomum cassia
- Commiphora myrrha
- Cordiceps sinensis
- Hypericum perforatum
- Larrea tridentate
- Ligusticum porteri
- Lomatium dissectum
- Melaleuca alternifolia
- Oleo europaea
- Usnea barbata
Adaptogen:
- Astragulus membranaceus
- Echinacea pallida, purpurea
- Eleutherococcus senticosus
- Ganderna lucidum
- Glycyrrhiza glabra
- Ligustrum lucidum
- Panax ginseng
- Panax quinquefolius
- Schisandra chinensis
- Withania somnifera
Lymph
- Ceanothus americanus
- Galium aparine
- Iris versicolor
- Phytolacca americana
Artemisia annua (annual wormwood) constituents
Sesquiterpene lactones, volatile oils
Artemisia annua (annual wormwood) actions
Anti-parasitic, anti-microbial, anti-neoplastic, bitter
Art’s mom, Anna, is pretty bitter!! Who gets malaria, worms and cancer at the same time? (indications & actions: Bitter, antimicrobrial, antiparasitic, antineoplastic). Good thing she’s iron tough!! (Combine with iron for optimal efficiency)
Artemisia annua (annual wormwood) Indicatons
Malaria, parasitic infection, cancer- leukemia and colon cancer
Artemisia annua (annual wormwood) s/e
May cause allergies or contact dermatitis
Think of ring worm rash for contact dermatitis and allergy
Artemisia annua (annual wormwood) CI
Potentially pregnancy and lactation; allergy to Astraceae family
Art’s mom, Anna, is pretty bitter. Who gets malaria, worms and cancer all at the same time? Good thing she is iron tough and NOt pregnant (CI).
Artemisia annua (annual wormwood) interactions
Combine with iron for optimal efficiency
Baptisia tinctoria (Wild indigo) Constituents
Water – soluble polysaccharide: arabinogalactans. Glycoproteins. Quinolizidine alkaloids: cystein, sparteine. Isoflavonoids. Hydroxycoumarins: scopoletine
Baptisia tinctoria (Wild indigo) pharmacology
Ethanol extract has significant positive effect on the phagocytosis of human erythrocytes. That has been found to raise the leukocyte count and to improve the endogenous defense reaction. An animal experimentation, polysaccharide and glycoprotein fraction demonstrated immune stimulating effect. Changes in mice showed an increase of phagocytosis activity of Kupffer’s cells, significant, dose dependent stimulation of lymphocytes and release of interleukin – one macrophages. Antiviral effects have been shown when used in combination with echinacea and thuja.
Baptisia tinctoria (Wild indigo) Actions
Immune stimulant, antimicrobial, anti-catarrhal, alternative
The Baptist woman named TORI (tincTORIa) had some wildly (Wild indigo) huge infected boobs. It all started with several URTI’s and tons of mucus (immune stim and antimicrobial, anti-catarrhal). Her fever got so high she was delerius and exhausted but eventually returned to her self (alterative).
Baptisia tinctoria (Wild indigo) indications
Upper respiratory infections with catarrh, pharyngitis, tonsillitis, mastitis, delirium with fever, chronic fatigue.
The Baptist woman named TORI had some wildly huge infected boobs. It all started with several URTI’s and lots of mucus. Her fever got so high she was delerius and exhausted but eventually she returned to her normal self..
Baptisia tinctoria (Wild indigo) s/e
G.I. irritation – nausea, vomiting
Wild Tori likes to party but always gets nauseas and vomits
Baptisia tinctoria (Wild indigo) CI
Long – term use, high dose, pregnancy and lactation
Baptisia tinctoria (Wild indigo) interactions
N/A
Commiphora myrrha (Myrrh) Constituents
Resins, gums, volatile oil, triterpenes, mucilage
Commiphora myrrha (Myrrh) Actions
Antimicrobial, antioxidant, anti-inflammatory, expectorant, antitussive
Com’on Mi PHORynx and Mouth hurts! (COM MI PHOR A Myrrh) And this damn cough makes me want honey but I can’t because it will mess with my diabetes. I guess I just have to suffer…myrrHA!!
Commiphora myrrha (Myrrh) indications
Inflammation of the mouth and pharynx for topical application. Used internally as an expectorant for coughs.
Commiphora myrrha (Myrrh) S/e
No health hazards reported with proper administration of therapeutic doses
Commiphora myrrha (Myrrh) CI
Not to be used during pregnancy and lactation
commiPhora for Pregnancy
Commiphora myrrha (Myrrh) Interactions
May potentiate insulin and hypoglycemic drugs – Metformin, glyburide, Rosiglitazone
Cordyceps sinensis (Catepillar fungus) Constituents
polysaccharides, unsaturated fatty acids, Oleic acid, linoleic fatty acids, amino acids
Cordyceps sinensis (Catepillar fungus) actions
Bronchodilator, antibiotic, anti-cancer
It’s a SIN if your SIS (SINenSIS) whips your husband with CORDs to try and treat his impotence from pancreatic cancer. When they get found out, he has an asthma attack and starts couging until he gets weak that you can stab him with a dirty knife right into his bones (protects bone marrow) where he bleeds out (anemia). You walk away thinking if the wound doesn’t kill him, the acute infection will!
Cordyceps sinensis (Catepillar fungus) Indications
Acute infection, anemia, protects bone marrow, fatigue, asthma, impotence, chronic cough, debility.
It’s a SIN if your SIS (SINenSIS) whips your husband with CORDs to try and treat his impotence from pancreatic cancer. When they get found out, he has an asthma attack and starts couging until he gets weak that you can stab him with a dirty knife right into his bones (protects bone marrow) where he bleeds out (anemia). You walk away thinking if the wound doesn’t kill him, the acute infection will!
Cordyceps sinensis (Catepillar fungus) s/e
Toxic doses: constipation, abdominal distention, or irregular menstruation, amenorrhea
Cordycep is a fungus- eat too much fungus will make your stomach bloat and constipation happens when you have SIFO.
Cordyceps may increase testosterone levels impacting menstruation
Cordyceps sinensis (Catepillar fungus) CI
N/A
Cordyceps sinensis (Catepillar fungus) interactions
Potentiates epinephrine
Your husband’s epinephrine was spiked when he was getting whiped with CORDs by your SIS.
hypericum perforatum – St. John’s wort constituents
Volatile oils; naphthodianthrones (hypericin); phloroglucinols (hyperforin), catechins; proanthocyananidins; flavonoids (rutin)
hypericum perforatum – St. John’s wort pharmacology
Comparable to trycyclic and SSRI, but with fewer side effects. Dose is dependent on inhibition of reuptake for noradrenaline and serotonin (5– HTP) at presynaptic axon membrane. Hyperforin may increase serotonin, lower cortisol and act and GABA receptors. Has antibacterial and anti-viral effects. Suppresses inflammation, leukocyte infiltration of wounds.
hypericum perforatum – St. John’s wort actions
Anti-inflammatory, astringent, Vulnerary, nervine, antimicrobial
hypericum perforatum – St. John’s wort Indications
Depression, anxiety. Inflammation of the skin, wounds and burns. Blunt injuries
hypericum perforatum – St. John’s wort s/e
High doses with exposure to UV light causes photo sensitivity rash, alopecia, diarrhea, indigestion, fatigue, depression, elevated liver enzymes
hypericum perforatum – St. John’s wort CI
Suicidal ideation, high doses and pregnancy
hypericum perforatum – St. John’s wort Interactions
Similar action to benzodiazepines (alprazolam, diazepam), tricyclic antidepressants (amitriptyline), may cause serotonin syndrome with SSRIs (fluoxetine), used to wean patients off MAOI’s (phenelzine) potentiates antiretrovirals (zidovudine), antagonizes theophylline, cyclosporine, digoxin, warfarin. INDUCES CYP450 3A4
Larrea tridentata (Chaparral) Constituents
Lignans, resins, flavonoids
Larrea tridentata (Chaparral) actions
Anti-inflammatory, anti-allergy, anti-microbial, antioxidant, anti-neoplastic, anti-spasmodic, expectorant
Larry (Larrea) and his buddies tried (trid) a Dave Chapparral (Chapparral) show where there were a lot of nice tata’s (tridenTATA). Everyone drank lots of strong tasting (s/e) liquor that defintiely damages some livers which can lead to cancer. (CI: Liver dz, s/e’s: hepatotoxicity). People were so drunk they all ended up sleeping with all the tata’s. When they woke in the morning, they all had herpes, infections and skin comlpaints. There was lots of nausea and vomiting (s/e) with SOB (respiratory problems)
Larrea tridentata (Chaparral) Indications
Topical: herpes simplex, respiratory problems (poultice), skin complaints wash
Internal: allergic rhinitis; cancer; infections caused by bacteria, yeast, larva, viruses, parasites
Larry (Larrea) and his buddies tried (trid) a Dave Chapparral (Chapparral) show where there were a lot of nice tata’s (tridenTATA). Everyone drank lots of strong tasting liquor that defintiely damages some livers and can cause cancer (CI: Liver dz, s/e’s: hepatotoxicity). People were so drunk they all ended up sleeping with all the tata’s. When they woke in the morning, they all had herpes, infections (Bacteria, yeast, larvae, viruses and parasites) and skin comlpaints. There was a lot of nausea and vomiting with SOB (respiratory problems) and runny noses (rhinitis).
Larrea tridentata (Chaparral) s/e
Strong taste, nausea, vomiting, jaundice, possibly hepatotoxicity. Possible contact dermatitis
Larrea tridentata (Chaparral) CI
Liver disease, topically on large areas of broken skin, pregnancy, lactation, high doses, long – term use
Larrea tridentata (Chaparral) Interactions
Caution with Hepatotoxic drugs, inhibits CYP 450
Ligusticum porteri (Osha) constituents
Alkaloids, saponins, phytosterols, essential oils
Ligusticum porteri (Osha) actions
Antimicrobial – infections in the respiratory tract. Antiviral, anti-septic. Stimulant, diaphoretic, carminative. Similar to lomatium dissectum.
Ligusticum porteri (Osha) indications
Remedy for upper and lower respiratory tract infections, including bronchitis, laryngitis. Viral infections – flu, fever, colds. Induces sweating
I swallowed my linguini (ligusticum) mushroom portibella (porteri) down the wrong pipe which made me sweat (diphoretic). Apparently, if you get fungus in the lungs, you’ll get a lung infection with fever, flu or cold. You’ll need to stimulate your immune system to beat it!
Ligusticum porteri (Osha) s/e
N/A
Ligusticum porteri (Osha) CI
Not to be used during pregnancy
Ligusticum porteri (Osha) Interactions
N/A
Lomatium dissectum (indian balsam) Constituents
Sesquiterpenes, volatile oils
Lomatium dissectum (indian balsam) actions
antiviral, antibacterial, fungicidal. Immune stimulant. anti-tussive, expectorant
Lomatium dissectum (indian balsam) indications
Viral respiratory infection. cough, colds, bronchitis, influenza, pneumonia, TB
Lomatium dissectum (indian balsam) s/e
Photosensitization; self-limiting measles like rash caused by resin
Don’t lay your lo MAT in the sun. You’ll burn and get red like a rash!
Lomatium dissectum (indian balsam) CI
Pregnancy. concurrent with UV therapy (skin rash)
Lomatium dissectum (indian balsam) Interactions
N/A
Melaleuca alternifolia (Tea Tree) constituents
Volatile oil: cineol (5%), terpinen-4-ol (40%), alpha-terpinene
Melaleuca alternifolia (Tea Tree) pharmacology
Tea tree causes auto lysis of bacteria during both exponential and stationary phase of bacterial cell growth. It’s effectiveness on the skin may also be attributed to its lipophilic nature causing it to penetrate the skin surface. Minimum bactericidal concentrations are typically close to 0.25% and many skin products range from one percent to 10%. Concentrations of tea tree oil greater than 300 MCG/ML had cytotoxic affects on fibroblasts and epithelial cells. Its action on staphylococcus aureus is most likely a membrane associated event. Tea tree oil inhibits cellular respiration and causes potassium leakage on E. coli cells, suggesting that it is a membrane active antibiotic.
Melaleuca alternifolia (Tea Tree) actions
antifungal, antimicrobial, antiseptic, immune stimulant
Melaleuca alternifolia (Tea Tree) indications
Topical: dermatophytosis (athlete’s foot), onychomycosis, acne, thrush, vaginitis
Staphylococcal skin infection, wounds, insect bites
Melaleuca alternifolia (Tea Tree) s/e
Burning sensation
Melaleuca alternifolia (Tea Tree) CI
Over large areas of broken skin, internal use
Melaleuca alternifolia (Tea Tree) Interactions
N/A
Oleu europea (Olive tree) constituents
Olive oil: Chief fatty acids: oleic acid (56-83%), palmitic acid, linoleic acid. Sterols: beta-sitosterol. Tocopherols.
Olive leaves: iridoid nonterpenes: oleoropine, oleoroside. Triterpenes: oleanolic acid, maslinic acid. Flavonoids, chalcones.