Bones 2

Question 1

osteoma defect where on bone

Answer 1

subperiosteal or endosteal cortex surface

Question 2

what type of bone is impacted with osteoma

Answer 2

woven and lamellar bone

Question 3

what is gardner syndrome

Answer 3

multiple osteomas

Question 4

compare sizes of osteoid and osteoblastoma

Answer 4

osteoid: less than 2 cm
osteoblastoma: greater than 2 cm

Question 5

can NSAIDS be used for relief of osteoid and osteoblastoma

Answer 5

osteoid: yes
osteoblastoma: no ``

Question 6

most common nonhematopoetic malignant primary bone tumor

Answer 6

osteosarcoma

Question 7

what is made in osteosarcoma?

Answer 7

osteoid

-painful enlarging mass

Question 8

what age groups are impacted by osteosarcoma

Answer 8

75% less than 20

elderly

Question 9

osteosarcoma is associated with what disease

Answer 9

paget’s disease

Question 10

what is Codman triangle

Answer 10

osteosarcoma tumor lifts periostium

Question 11

where does osteosarcoma usally occur on bone

Answer 11

metaphysis medulla, knee

Question 12

osteosarcoma: hereditary retinoblastoma is a defect in what gene

Answer 12

RB

Question 13

osteosarcoma: Li-Fraumeni syndrome defect in

Answer 13

p53

Question 14

osteosarcoma metastazies where

Answer 14

lung

Question 15

Osteochondroma exostosis what happens

Answer 15

mushroom-shaped cartilage-capped

Question 16

where does Osteochondroma exostosis occur

Answer 16

metaphysis: near growth plate of long tubular bones, especially around knee

Question 17

Osteochondroma exostosis: multple heredity exotosis isa defect in what gene and how is passed on

Answer 17

EXT1 and EXT2

autosomal dominant

Question 18

how fast does osteochondrom grow? pain? increases risk for what

Answer 18

slow growing, stops with closure of growth plate

- Multiple Hereditary exostosis

Question 19

Chondroma is what

Answer 19

benign hyaline cartilage tumor

Question 20

where is enchondroma

Answer 20

phalynx

Question 21

where does subperiotsteal chondroma occur

Answer 21

surface of bone

Question 22

what does enchondroma look like

Answer 22

less than 3cm grey-blue

nodules of hyaline cartilage with peripheral enchondral ossification

Question 23

enchondroma is a risk of turning into

Answer 23

Enchondromatosis ( Ollier disease)

Maffucci syndrome: enchondromas with hemangiomas

Question 24

most common place for enchondroma tumor

Answer 24

phalynx

Question 25

chondroblastoma is seen in what age group

Answer 25

teenagers

Question 26

chondroblastoma most common place found where on body

Answer 26

KNEE EPIPHYSIS

Question 27

define chondrosarcoma

Answer 27

no malignant bone formation

Question 28

where does chondrosarcoma occur

Answer 28

intramedullary | juxtacortical and surface

Question 29

histo of chondrosarcoma

Answer 29

clear cell differentiated mesynchymal

Question 30

what are the 3 patterns for fibrous dyspasia

Answer 30

monostotic - polystotic with soft tissue myxomas - polyostotic with endocrine dysfunction

Question 31

what does the X-ray look like for fibrous dysplasia

Answer 31

ground glass and well-demarcated

Question 32

where on bone does fibrous dysplasia occur

Answer 32

diaphysis

Question 33

fibrous dysplasia: monostatic where does it usually occur? who does it occur in

Answer 33

ribs femur tibia | teens

Question 34

fibrous dysplasia: polyostatic, is what two diseases

Answer 34

Mazabraud syndrome | McCune-Albright syndrome

Question 35

fibrous dysplasia: McCune-Albright syndrome? clinical presentaiotn endocrine?

Answer 35

cafe au lait skin pigmentations | sexual precocity, hyperthyroidism

Question 36

fibrous dysplasia histo

Answer 36

chinese character woven bone in fibrous stroma

Question 37

what is Ewing Sarcoma family

Answer 37

small round blue cell tumor of bone and soft tissue

Question 38

gene translocation for ewing sarcoma

Answer 38

T(11;22) | EWS-FLI1

Question 39

Ewing occurs where in bone

Answer 39

medullary cavitity but invades cortex into soft tissue | - dipahysis of long bone

Question 40

other symptoms with Ewing

Answer 40

fever, anemia, leukocytosis

Question 41

what is giant cell tumor of bone

Answer 41

benign locally aggressive tumor of macrophage/monocyte system

Question 42

mononuclear cells have what receptor

Answer 42

RANKL

Question 43

where on bone does giant cell tumor occur

Answer 43

epiphysis may extend to metaphysis

Question 44

most common location of ewing

Answer 44

knee

Question 45

Aneurysmal bone cyst (ABC)

Answer 45

multiloculated blood-filled cysts

Question 46

where does Aneurysmal bone cyst (ABC) occur

Answer 46

metaphysis of long bones and vertebrae

Question 47

most common form of skeletal malignancy

Answer 47

metastatic disease

Question 48

how can metastatic disease spread to bone

Answer 48

direct lymph or hematogenous -intraspinal ( batson plexus of veins)

Question 49

bone tumors of metaphysis

Answer 49

``` osteoid osteoma osteochondroma osteosarcoma chondroma fibrous dysplasia fibrous cortical defect ABC ```

Question 50

bone tumor on epiphysis

Answer 50

clear cell chondrosarcoma | chondroblastoma

Question 51

bone tumor on diaphysis

Answer 51

ewing sarcoma | firbous dysplaisa

Question 52

bone tumor on epiphysis/metaphysis

Answer 52

giant cell tumor aneurysmal bone cyst