Bacterial Zoonoses Flashcards

1
Q

Leptospira is accociated with what host and can live where

A

animal host

- survive in fresh water, tropics

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2
Q

how Leptospira transmitted

A
  • through abrasion of skin

- direct or indirect urine from infected animals or fluids

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3
Q

what type of people get Leptospira

A

triathlons
swimmers
sewer workers

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4
Q

Where in the world is Leptospira found

A

tropical regions

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5
Q

Clinical manifestations of Leptospira

A

flue

Weil syndrome: jaundice, renal dysfunction

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6
Q

what happens in the biphasic clinical manifestations

A

1st: septicemis
2nd: immune mediated

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7
Q

treatment for Leptospira mild? severe?

A

Doxycycline

Severe: IV penicillin

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8
Q

Franceisella tularensis strains what kind of bacteria

A

gram negative

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9
Q

major source of Fanceisella turnarensis in US

A

Ticks and rabbits

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10
Q

name two ways of transmission to humans f. Tularensis

A

inhalation

skin/mucous contact

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11
Q

what are hotspots for Franceisella tularensis in US

A

Oklahoma, arkansas and Missouri and on NE coast

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12
Q

Clinical manifestations of Franceisella Tularensis

A

Ulceroglandular

lymphadenitis

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13
Q

lab diagnosis for Franciesella tularensis

A

Culture
serology
microscopy

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14
Q

what drugs are used to treat Franciesella tularensis

A

Streptomycin

Gentamicin

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15
Q

Brucella is what type of bacteria and shape

A

gram negative

coccobacilli

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16
Q

where does Brucellosis replicate

A

intracellular, replicates reticuloendothelial system

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17
Q

what is world side distribution of Brucelleosis

A

Latin America
Middle East
Africa

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18
Q

where in the US does Brucellosis occur? in what products in the US can it be found

A

CA and TX

-unpasteurized milk and diary

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19
Q

clinica manifestations of Brucellosis

A

Undulant fever

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20
Q

lab diagnosis for Brucellosis

A

Serology
Cultures
bone marrow cultures ( can confrim)
microscopy

21
Q

Treatment for Brucella

A

Doxycycline and Rifampin for at least 6 weeks

22
Q

Yersinia Pestis is what type of bacteria

A

gram negative

23
Q

how does Yersinia pestis stain

A

bipolar staining bacillus

safety pin appearance on gram stain and Wayson stain

24
Q

who carie Yersinia pestis in us

A

Rodents and fleas

25
what are manifestastions of Yersinia Pestis
Bubonic: buboes primary septicemic: DIC pneuomic: everyone dies
26
Yersinia Pestis is very senstive to what lab diagnosis test
Immunofluorescent stain
27
what other Lab diagnosis is used for Yersinia pestis
Serology Genotyping PCR
28
Treatment for Plaque
Tetracycline, Chloramphenicol ( Meningitis) Streptomycin , gentamacin
29
what do you treat people with if they come in close contact with someone with Plague
Doxycycline
30
Common name for Coxiella burnetti
Q fever
31
what type of bacteria is Coxiella Burnetti
gram negativ
32
where does Coxiella Burnetti replicate
strict intracellular
33
how can people get Coxiella Burnettii
Inhalation | - unpasteurized diary products
34
what are acute symptoms for Coxiella Burnetti? treatment
heachache fever pneumonia -Doxycycline
35
what are chronic symptoms for Coxiella burnetti? Treatment
subacute endocarditis | -Doxycycline and hydroxychloroquine
36
Bartonella Henselae is what type of bacteria
gram negative
37
what is reservoir for Bartonella Henselae
cats and fles
38
Bartonella Henselae can cause what disease
cat-scratch disaese
39
Cat-scratch disease commonly in who
children
40
clinical manifestations for Cat-scratch
lymphadenopathy of nodes | fever
41
what bacteria causes cat-sratch in immunocompromised patient
bacillary angiomatosis
42
how is Cat scratch treated
self-limited but | Azithromycin, ciprofloxacin, TMP-SMX
43
Pasteurella multicida and canis
cat and dog bite
44
when an animal bites for Pasteurella when does clinical symptoms appeasrs
typical clinical picture of rapidly-developing cellulitis after bites ( within 24 hours)
45
Paterurella is resistant to what medicine
clindamycin | - 1st generation cephalosporins
46
treatment for Pasteurella
penicillin with Amoxicillin-clavulanic
47
Eikenella, you get it from what type of bites
human
48
where does Eikenella corroden colonize
human oropharynx