Bacterial Zoonoses Flashcards
Leptospira is accociated with what host and can live where
animal host
- survive in fresh water, tropics
how Leptospira transmitted
- through abrasion of skin
- direct or indirect urine from infected animals or fluids
what type of people get Leptospira
triathlons
swimmers
sewer workers
Where in the world is Leptospira found
tropical regions
Clinical manifestations of Leptospira
flue
Weil syndrome: jaundice, renal dysfunction
what happens in the biphasic clinical manifestations
1st: septicemis
2nd: immune mediated
treatment for Leptospira mild? severe?
Doxycycline
Severe: IV penicillin
Franceisella tularensis strains what kind of bacteria
gram negative
major source of Fanceisella turnarensis in US
Ticks and rabbits
name two ways of transmission to humans f. Tularensis
inhalation
skin/mucous contact
what are hotspots for Franceisella tularensis in US
Oklahoma, arkansas and Missouri and on NE coast
Clinical manifestations of Franceisella Tularensis
Ulceroglandular
lymphadenitis
lab diagnosis for Franciesella tularensis
Culture
serology
microscopy
what drugs are used to treat Franciesella tularensis
Streptomycin
Gentamicin
Brucella is what type of bacteria and shape
gram negative
coccobacilli
where does Brucellosis replicate
intracellular, replicates reticuloendothelial system
what is world side distribution of Brucelleosis
Latin America
Middle East
Africa
where in the US does Brucellosis occur? in what products in the US can it be found
CA and TX
-unpasteurized milk and diary
clinica manifestations of Brucellosis
Undulant fever
lab diagnosis for Brucellosis
Serology
Cultures
bone marrow cultures ( can confrim)
microscopy
Treatment for Brucella
Doxycycline and Rifampin for at least 6 weeks
Yersinia Pestis is what type of bacteria
gram negative
how does Yersinia pestis stain
bipolar staining bacillus
safety pin appearance on gram stain and Wayson stain
who carie Yersinia pestis in us
Rodents and fleas
what are manifestastions of Yersinia Pestis
Bubonic: buboes
primary septicemic: DIC
pneuomic: everyone dies
Yersinia Pestis is very senstive to what lab diagnosis test
Immunofluorescent stain
what other Lab diagnosis is used for Yersinia pestis
Serology
Genotyping
PCR
Treatment for Plaque
Tetracycline, Chloramphenicol ( Meningitis) Streptomycin , gentamacin
what do you treat people with if they come in close contact with someone with Plague
Doxycycline
Common name for Coxiella burnetti
Q fever
what type of bacteria is Coxiella Burnetti
gram negativ
where does Coxiella Burnetti replicate
strict intracellular
how can people get Coxiella Burnettii
Inhalation
- unpasteurized diary products
what are acute symptoms for Coxiella Burnetti? treatment
heachache
fever
pneumonia
-Doxycycline
what are chronic symptoms for Coxiella burnetti? Treatment
subacute endocarditis
-Doxycycline and hydroxychloroquine
Bartonella Henselae is what type of bacteria
gram negative
what is reservoir for Bartonella Henselae
cats and fles
Bartonella Henselae can cause what disease
cat-scratch disaese
Cat-scratch disease commonly in who
children
clinical manifestations for Cat-scratch
lymphadenopathy of nodes
fever
what bacteria causes cat-sratch in immunocompromised patient
bacillary angiomatosis
how is Cat scratch treated
self-limited but
Azithromycin, ciprofloxacin, TMP-SMX
Pasteurella multicida and canis
cat and dog bite
when an animal bites for Pasteurella when does clinical symptoms appeasrs
typical clinical picture of rapidly-developing cellulitis after bites ( within 24 hours)
Paterurella is resistant to what medicine
clindamycin
- 1st generation cephalosporins
treatment for Pasteurella
penicillin with Amoxicillin-clavulanic
Eikenella, you get it from what type of bites
human
where does Eikenella corroden colonize
human oropharynx
