Bacterial Zoonoses Flashcards

1
Q

Leptospira is accociated with what host and can live where

A

animal host

- survive in fresh water, tropics

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2
Q

how Leptospira transmitted

A
  • through abrasion of skin

- direct or indirect urine from infected animals or fluids

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3
Q

what type of people get Leptospira

A

triathlons
swimmers
sewer workers

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4
Q

Where in the world is Leptospira found

A

tropical regions

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5
Q

Clinical manifestations of Leptospira

A

flue

Weil syndrome: jaundice, renal dysfunction

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6
Q

what happens in the biphasic clinical manifestations

A

1st: septicemis
2nd: immune mediated

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7
Q

treatment for Leptospira mild? severe?

A

Doxycycline

Severe: IV penicillin

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8
Q

Franceisella tularensis strains what kind of bacteria

A

gram negative

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9
Q

major source of Fanceisella turnarensis in US

A

Ticks and rabbits

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10
Q

name two ways of transmission to humans f. Tularensis

A

inhalation

skin/mucous contact

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11
Q

what are hotspots for Franceisella tularensis in US

A

Oklahoma, arkansas and Missouri and on NE coast

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12
Q

Clinical manifestations of Franceisella Tularensis

A

Ulceroglandular

lymphadenitis

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13
Q

lab diagnosis for Franciesella tularensis

A

Culture
serology
microscopy

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14
Q

what drugs are used to treat Franciesella tularensis

A

Streptomycin

Gentamicin

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15
Q

Brucella is what type of bacteria and shape

A

gram negative

coccobacilli

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16
Q

where does Brucellosis replicate

A

intracellular, replicates reticuloendothelial system

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17
Q

what is world side distribution of Brucelleosis

A

Latin America
Middle East
Africa

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18
Q

where in the US does Brucellosis occur? in what products in the US can it be found

A

CA and TX

-unpasteurized milk and diary

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19
Q

clinica manifestations of Brucellosis

A

Undulant fever

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20
Q

lab diagnosis for Brucellosis

A

Serology
Cultures
bone marrow cultures ( can confrim)
microscopy

21
Q

Treatment for Brucella

A

Doxycycline and Rifampin for at least 6 weeks

22
Q

Yersinia Pestis is what type of bacteria

A

gram negative

23
Q

how does Yersinia pestis stain

A

bipolar staining bacillus

safety pin appearance on gram stain and Wayson stain

24
Q

who carie Yersinia pestis in us

A

Rodents and fleas

25
Q

what are manifestastions of Yersinia Pestis

A

Bubonic: buboes
primary septicemic: DIC
pneuomic: everyone dies

26
Q

Yersinia Pestis is very senstive to what lab diagnosis test

A

Immunofluorescent stain

27
Q

what other Lab diagnosis is used for Yersinia pestis

A

Serology
Genotyping
PCR

28
Q

Treatment for Plaque

A

Tetracycline, Chloramphenicol ( Meningitis) Streptomycin , gentamacin

29
Q

what do you treat people with if they come in close contact with someone with Plague

A

Doxycycline

30
Q

Common name for Coxiella burnetti

A

Q fever

31
Q

what type of bacteria is Coxiella Burnetti

A

gram negativ

32
Q

where does Coxiella Burnetti replicate

A

strict intracellular

33
Q

how can people get Coxiella Burnettii

A

Inhalation

- unpasteurized diary products

34
Q

what are acute symptoms for Coxiella Burnetti? treatment

A

heachache
fever
pneumonia
-Doxycycline

35
Q

what are chronic symptoms for Coxiella burnetti? Treatment

A

subacute endocarditis

-Doxycycline and hydroxychloroquine

36
Q

Bartonella Henselae is what type of bacteria

A

gram negative

37
Q

what is reservoir for Bartonella Henselae

A

cats and fles

38
Q

Bartonella Henselae can cause what disease

A

cat-scratch disaese

39
Q

Cat-scratch disease commonly in who

A

children

40
Q

clinical manifestations for Cat-scratch

A

lymphadenopathy of nodes

fever

41
Q

what bacteria causes cat-sratch in immunocompromised patient

A

bacillary angiomatosis

42
Q

how is Cat scratch treated

A

self-limited but

Azithromycin, ciprofloxacin, TMP-SMX

43
Q

Pasteurella multicida and canis

A

cat and dog bite

44
Q

when an animal bites for Pasteurella when does clinical symptoms appeasrs

A

typical clinical picture of rapidly-developing cellulitis after bites ( within 24 hours)

45
Q

Paterurella is resistant to what medicine

A

clindamycin

- 1st generation cephalosporins

46
Q

treatment for Pasteurella

A

penicillin with Amoxicillin-clavulanic

47
Q

Eikenella, you get it from what type of bites

A

human

48
Q

where does Eikenella corroden colonize

A

human oropharynx